Jobs · Engineering · California

Senior/Staff Optical Engineer

QuantumCell · South San Francisco, CA · Yesterday
On-siteEngineeringFull-time

About QuantumCell

We are a dynamic tech company in the biology space on a mission to decode and defeat the most complex brain disorders of our time. By converging next-generation sensing technologies, autonomous robotics, and cutting-edge AI, we are building the world's first high-fidelity virtual cell and virtual system model: a mechanistically anchored simulation of human biology that can predict how drugs will behave in a patient before a single trial is run.

Role Summary

We are seeking an exceptional, forward-thinking Senior or Staff Optical Engineer to design and implement Raman Spectroscopy methods for characterization of biological samples. This is a hands-on role at the core of our quantum sensing team — working with other team members to implement innovative ideas into benchtop setups for testing real samples.

Responsibilities

  • Design, procure, set up, and conduct optical testing on biological samples
  • Perform optical alignment for complex optical systems such as high-resolution microscope and Raman spectroscopy
  • Develop specifications for components, subsystems etc. and work with suppliers to procure such
  • Work with firmware/software engineers to set up computer-controlled tests
  • Analyze test results and generate test reports for internal and external stakeholders
  • Generate design documents and test procedures
  • Collaborate with cross-functional teams to meet business goals

Requirements

  • Bachelor’s Degree (or equivalent) in engineering, physics, or a related field, with significant experience in optical systems - 5 years of experience (PhD and Postdoc experience are acceptable).
  • Hands-on experience in optical system design, alignment and tests
  • Experience in high resolution microscopy and/or Raman Spectroscopy is a plus
  • Hands-on experience in building laser-based optical test setup that includes laser sources, beam shaping optics, detection sensors/cameras, controllers and data acquisition instruments
  • Proven track record of conducting independent tests and delivering test results
  • Comfort working at the interface of biology and emerging technologies
  • Experience collaborating with automation or software engineers to design experiments that generate model-ready data
  • A startup company mindset: comfortable operating in a fast-moving, early-stage environment where you'll help define processes, not just follow them
  • Strong communication skills and the ability to collaborate across functions

Qualifications

  • Experience in optical engineering and systems design
  • Knowledge of Raman spectroscopy principles and applications
  • Experience with high-resolution microscopy techniques
  • Ability to work independently and manage multiple projects
  • Strong analytical and problem-solving skills

Skills

  • Optical system design and alignment
  • Raman spectroscopy expertise
  • High-resolution microscopy techniques
  • Project management and organizational skills
  • Collaboration with cross-functional teams

Benefits

  • Competitive compensation package (salary, equity, bonus) based on experience
  • Comprehensive medical, dental, and vision benefits
  • Access to world-class scientific collaborators and leading computational infrastructure, including large-scale GPU clusters and proprietary biological datasets of exceptional scale and resolution
  • A unique opportunity to help define how AI learns from biology at one of the most ambitious companies in CNS drug discovery
  • The chance to contribute to a deeply mission-driven organization focused on transforming patient outcomes and advancing treatments for complex diseases
  • Support for conference attendance and active participation in the scientific community
  • A collaborative, inclusive, and fun culture where you’ll play a key role in building the team, shaping the environment, and driving meaningful impact from the ground up

How to Apply

Send your CV to: careers@qcell.ai

We are an equal opportunity employer.

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