Senior Scientist, Protein Analytical Development, Characterization

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity.

About Innovative Medicine

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow. Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

Purpose

The Therapeutics Development and Supply, Protein Development, Analytical Development organization is recruiting a highly skilled and motivated Senior Scientist to join our Protein Analytical Development Characterization group. The role reports to the Scientific Director within the Characterization group and will lead development, design, and execution of mass spectrometry assays in support of product characterization and process development of protein-based therapeutics. The successful candidate will play a key role in advancing innovative analytical technologies and delivering phase-appropriate characterization across clinical development and commercialization to ensure the successful advancement of our therapeutic portfolio.

Responsibilities

• Develop, design, and perform mass spectrometry assays in support of product characterization and process development activities for protein and protein conjugates.
• Drive innovation by evaluating and implementing emerging analytical technologies to enhance characterization strategies.
• Serve as a key technical contributor on cross-functional project teams, leading scientific discussions and providing analytical expertise to support project objectives.
• Maintain accurate laboratory documentation and author protocols, technical reports, and regulatory-supporting documents in compliance with Good Manufacturing Practice (GMP) requirements.

Requirements

• Minimum of a Master’s degree is required; PhD is highly preferred.
• Minimum of 4 years’ experience following the completion of a Master’s degree or 0-2 years’ experience following the completion of a PhD in Analytical Chemistry, Biochemistry, Pharmaceutical Sciences, or a related field.
• Hands-on experience with Mass Spectrometry (intact mass analysis, peptide mapping, etc.).
• Experience working with protein/antibody.

Preferred Skills

• Experience with 3rd party MS software (e.g., Protein Matrix, Genedata Expressionist, etc.).
• Experience working with antibody drug conjugate.
• Experience working in a GLP/GMP environment.
• Experience and understanding of pharmaceutical development CMC and regulatory requirements for protein biologics.

Location: Malvern, Pennsylvania, United States of America