Senior Scientist, Medicinal Chemistry, Integrated Drug Discovery

Main Responsibilities

• Design and synthesize small molecule targets to drive programs to clinical candidate nomination.
• Use reaction and reagent databases to select effective methods/routes to maximize productivity and provide solutions to complex multi-step synthetic problems.
• Prepare and characterize high purity target compounds and intermediates to meet aggressive project timelines.
• Proficiency with the use of analytical techniques for structural characterization and ability to interpret complex NMR spectra.
• Register compounds in corporate database and maintain notebooks according to SOP.
• Champion new chemistry techniques, reagents and methodology in discovery chemistry and participate in group/lab responsibilities.
• Understand project SAR, adapt and prioritize work proactively based on emerging data.
• Interpret biological data (DMPK, pharmacology, safety) to contribute to project advancement.
• Able to work independently, proactively and collaboratively with other team members to design compounds to address key issues.
• Dedication to lifelong learning.
• Provide formal and informal mentoring to junior staff members.
• Determine the relevance of patent search results and assess the patentability of new targets.
• Assist with filing patent applications by reviewing claims and providing experimental data.
• Communicate and interact with other staff members in a professional and courteous manner.
• Operate in the lab in a safe and efficient manner according to HSE guidelines and adhere to all mandatory company compliance requirements.
• Adapt to changes and challenges in a productive and professional manner.
• Act as an ambassador for the department and attend appropriate scientific meetings to stay up to date with current literature and industry direction.

About You

• Education & Experience:
  • Bachelors Degree in chemistry or related field with minimum 7 years of relevant research experience in an academic or biopharmaceutical setting
  • ORMasters Degree with minimum 4 years of relevant research experience in an academic or biopharmaceutical setting
  • ORPhD with minimum 2 years of relevant research experience in an academic or biopharmaceutical setting
• Deep knowledge of organic chemistry and a growing understanding of medicinal chemistry principles.

Why Choose Us?

• Bring the miracles of science to life alongside a supportive, future-focused team.
• Discover endless opportunities to grow your talent and drive your career, whether its through a promotion or lateral move, at home or internationally.
• Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.
• Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks gender-neutral parental leave.
• Be part of a pioneering biopharma company that engages patients early in drug development and uses their insights to design studies that reflect real-world needs.
• Help improve the lives of millions of people globally by making drug development quicker and more effective.
• Work at the forefront of drug discovery, harnessing cutting-edge AI, data, and digital platforms to push the boundaries of science.