Senior Scientist II Discovery Bioanalysis, PK Sciences

About the role

This role is based in Cambridge, MA. Novartis is unable to offer relocation support for this role: please only apply if this location is accessible for you.

Key responsibilities

• Provide internal lab based bioanalytical support investigating the PK/TK properties of low molecular weight and novel modality compounds.
• Responsible for setting up the new LC-MS workflow by engaging with the key stakeholders.
• Provide mentorship and insights for junior associates to support advance method development for custom discovery PK and PKPD.
• Collaborate as a subject matter expert in bioanalysis with biotransformation, in vitro and in vivo colleagues, as well as chemists and biologists with project teams.
• Independently conceive and run complex experiments/workflows that implement project strategy.
• Analyze, write reports and communicate own results in the project meetings.
• Implement technologies such as LC-MS/MS, SFC-MS/MS or LC-HRMS for low molecular weight and novel modality compounds.
• Explore automation and software related solutions to increase workflow efficiency.
• Collaborate with our CRO partners for special case custom BA method transfers to the CRO.
• Utilize established networks and build new network connections, including outside of own department.
• Comply with local and Novartis-specific rules and regulations.

Essential requirements

• B.S. (6+ years) or M.S. (4+ years) or PhD degree (1+ years) of bioanalytical lab scientist in biotech or pharma industry.
• Agility to independently perform high quality and fit-for-purpose bioanalysis within short timelines. Emerging scientific leader with good values and behaviors.
• Hands on experience in custom method development, variety of sample preparation (SPE, LLE, IMC etc.) and quantitative analytical methods for LC-MS (low- and high-resolution) are required.
• Agility to adapt and shift priorities as per business needs.
• Practices efficient time management to work under tight timelines, focuses on deliverables, and effectively prioritize when designing/undertaking experimental plan.
• High motivation, curiosity and creativity and the ability to thrive in a matrixed work environment and communicate effectively within multidisciplinary teams.
• Good oral and written communication and presentation skills to communicate key results to internal teams.

Desirable requirements

• Experience with BA data analysis and reporting PK/TK data is highly preferred.
• Proven track record of establishing new lab workflows is preferred.

Pay

The salary for this position is expected to range between $98,700 and $183,300 per year.

Schedule

Not specified.

Benefits

Your compensation will include a performance-based cash incentive and, depending on the level of the role, eligibility to be considered for annual equity awards.

To learn more about the culture, rewards and benefits we offer our people click here.

EEO Statement

The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, sex, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status.