Senior Scientist I/II, Process Engineering

About the Role

Process Engineering, part of AbbVie R&D’s Small Molecule CMC Development organization, designs and develops scalable processes for small molecule drug substances and drug products, including antibody drug conjugates (ADCs), throughout pre-clinical and clinical development stages. The team also partners with Biologics CMC Development and Aesthetics R&D to provide active engineering support for robust process scale-up and manufacturing of biologics drug substances and drug products, including toxins and cosmetic active ingredients (CAIs).

The successful candidate will play a key role in the Center of Excellence in Crystalline Drug Substance and Drug Product (CrySP), focusing on crystallization fundamentals and process development. The role involves developing isolation and purification strategies for small and large molecule compounds, leading novel technology development, and collaborating across functions to address process challenges.

Responsibilities

• Develop robust scale-up and manufacturing processes for small and/or large molecule assets through all phases of development.
• Perform laboratory experiments and process modeling to support process understanding and optimization.
• Address challenging problems in separations and isolations using expertise in thermodynamics, crystallization fundamentals, transport phenomena, and mathematical modeling.
• Author and/or review technical documents summarizing process development efforts.
• Collaborate across multidisciplinary teams, including organic chemists, analytical chemists, process development engineers, pilot plant engineers, drug product development scientists, program managers, and regulatory affairs specialists.
• Communicate findings and recommendations effectively.
• Author publications and present at scientific conferences.

Qualifications

• BS, MS, or PhD in Chemical Engineering or a related field.
• 10+ years of relevant industrial experience (BS), 8+ years (MS), or 0+ years (PhD). Job level will be commensurate with academic and/or industrial work experience.
• Strong background in chemical engineering with a proven ability to demonstrate skills in this field.
• Ability to learn, understand, and master new experimental techniques.
• Effective oral and written communication skills.
• Strong team player with a collaborative nature.

Benefits

• Comprehensive package including paid time off (vacation, holidays, sick).
• Medical, dental, and vision insurance.
• 401(k) retirement plan.
• Eligibility to participate in long-term incentive programs.

Applicable only to applicants in locations with pay disclosure requirements: Compensation is determined based on job grade, geographic location, and other factors. This role may be eligible for bonuses, commissions, or other discretionary incentives consistent with applicable law.