Senior Scientist I / II - Biologics Analytical R&D

About the role

The biologics early analytical development group develops state-of-the-art analytical techniques for analysis of therapeutic proteins and other novel biologic molecules using separation science and other biophysical techniques. We are looking for diverse candidates with strong scientific and leadership experience to join the AbbVie Analytical R&D team and can offer exciting and rewarding career opportunities for these candidates.

Responsibilities

• Effectively function as a scientist, generating original technical ideas and research or development strategies.
• Demonstrate the ability to resolve key project hurdles and assumptions by effectively utilizing available information and technical expertise.
• Independently responsible for project science within his/her area of expertise on one or more project teams leading the method development and validation for complex biologic therapeutics.
• Proactively seek out new information in the literature and incorporate this into individual projects as well as the overall program.
• Work in partnership with colleagues from Discovery, Process Chemistry/Engineering Formulation Development, and Characterization departments, among others.

Requirements

• Ph.D. degree in Biochemistry, Analytical Chemistry, Pharmaceutical Sciences or a closely related discipline or MS degree with 8 years of experience.
• Qualification for Senior Scientist I: Ph.D. with 0-4 years of experience is required with relevant experience or MS with 8 years of experience.
• Qualification for Senior Scientist II: Ph.D. with 4+ years of experience is required with relevant experience or MS with 10 years of experience.
• Practical experience and strong knowledge in one or more of the following areas: protein/oligonucleotide HPLC, capillary electrophoresis, MALS, automation and/or spectroscopy for biologics.
• Previous cGMP or GLP experience and attention to detail in documentation.
• Demonstrated record of independent thought, creativity and scientific accomplishment (e.g. peer reviewed journal publications, patents).
• A solid understanding of protein/oligonucleotide chemistry and biochemistry, particularly as related to biologics drug development.
• Strong data and time organization/management skills coupled with strong interpersonal and effective communication skills for facilitating collaborations with a demonstrated ability to lead cross functional process development teams.
• Effective writer and communication of research or other regulatory materials.
• Experience with analytical Multivariate Analytical Procedures development and/or validation a plus.

Qualifications

• Ph.D. degree in Biochemistry, Analytical Chemistry, Pharmaceutical Sciences or a closely related discipline or MS degree with 8 years of experience.
• Qualification for Senior Scientist I: Ph.D. with 0-4 years of experience is required with relevant experience or MS with 8 years of experience.
• Qualification for Senior Scientist II: Ph.D. with 4+ years of experience is required with relevant experience or MS with 10 years of experience.
• Practical experience and strong knowledge in one or more of the following areas: protein/oligonucleotide HPLC, capillary electrophoresis, MALS, automation and/or spectroscopy for biologics.
• Previous cGMP or GLP experience and attention to detail in documentation.
• Demonstrated record of independent thought, creativity and scientific accomplishment (e.g. peer reviewed journal publications, patents).
• A solid understanding of protein/oligonucleotide chemistry and biochemistry, particularly as related to biologics drug development.
• Strong data and time organization/management skills coupled with strong interpersonal and effective communication skills for facilitating collaborations with a demonstrated ability to lead cross functional process development teams.
• Effective writer and communication of research or other regulatory materials.
• Experience with analytical Multivariate Analytical Procedures development and/or validation a plus.

Skills

• Proven experience in developing and validating analytical methods for complex biologics.
• Knowledge of protein/oligonucleotide chemistry and biochemistry, particularly as related to biologics drug development.
• Ability to work independently and lead cross-functional teams.
• Strong data management and organizational skills.
• Excellent written and verbal communication skills.
• Experience with chromatography, electrophoresis, spectroscopy, and automation techniques.

Benefits

• Paid time off (vacation, holidays, sick)
• Medical/dental/vision insurance
• 401(k) plan

Pay

Compensation range is determined based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location.

Schedule

Full-time position.