Senior Scientist, Bioanalytical Science

Responsibilities

• Support the development and optimization of bioanalytical methods (e.g. LC/MS) to evaluate concentration of API, metabolites, and related species across multiple small and large animal species
• Manage execution of method development and sample analysis across multiple external CROs and collaborators
• Aid in the design and selection of methods of sample extraction and analysis across a range of matrices including lymph, plasma, and solid tissues
• Contribute to the development or application of relevant pharmacokinetic models to add fundamental understanding where appropriate
• Contribute to day-to-day research activities with increasing independence while ensuring alignment with departmental and company priorities
• Coordinate bioanalytical laboratory operations including maintenance and sourcing of laboratory equipment, interfacing with lab safety or operations teams, and supply/inventory management

Qualifications

• MS/PhD degree in analytical chemistry, bioanalytical chemistry, pharmaceutical analysis with 3+ years for PhD, or 8+ years for MS
• Track record of supporting the development and validation of bioanalytical LC-MS/MS methods designed at standards ranging from "fit-for-purpose" through GLP
• Analysis of prodrugs and associated species highly desirable
• Hands-on familiarity running and maintaining industry-standard mass spectrometry instrumentation
• Understanding of FDA and global regulatory requirements of study types assigned, as well as Testing Facility SOPs and Good Laboratory Practices (GLPs), as appropriate
• Highly motivated and results driven individual with a passion for working in a fast-paced and evolving organization
• Experience with CROs and managing outsourced studies critical
• Outstanding communication, interpersonal, and partnering skills
• Excellent cross-disciplinary skills in communicating scientific ideas to non-scientist stakeholders to foster collaboration and deliverable-based teamwork
• Startup experience is highly valued
• Ability to adjust rapidly to changing scientific priorities and technologies