Senior Research Scientist; Analytical Development

Responsibilities

• Develop and utilize characterization techniques to support drug substance and drug product development.
• Provide expertise and timely support for solid-state techniques, which will include but is not limited to XRPD, PSD, DSC, TGA, SEM and DVS.
• Independently perform hands-on experimental work utilizing the above instrumentation.
• Perform as well as oversee laboratory experiments in the areas of crystallization process development and solid form screening of pharmaceutical compounds including but not limited to polymorph, salt, cocrystal, crystallization and solid dispersion screens.
• Convey experimental and analytical results to clients in data summaries and reports.
• Maintain appropriate documentation (records and lab notebooks).
• Meet timelines for delivering on clients' expectations.
• Communicate clearly and accurately with internal and external clients, both verbally and through written data summaries and reports.
• Design experimental plans and write appropriately scoped proposals for clients.
• Provide expert scientific review of highly technical reports for clients.
• Recommend and implement procedures and techniques to increase the quality of solid form screening services.
• Regularly interact with other Curia colleagues (including sales, marketing, procurement, etc.) to provide the best possible service to clients.
• Comply with cGMP procedures, safety requirements, and company policies.
• Mentor, train, and supervise junior members of the group.
• Comply with all cGMP and safety requirements, laboratory SOPs, and company policies and procedures.
• Provide project oversight, client interactions, and expert scientific consulting.
• Develop and write analytical methods and operating procedures according to specific sample or testing requirements.
• Maintain XRD instrumentation per written GMP procedures to ensure optimal operations and quality data generation.
• Prepare expertly written scientific reports, proposals, and internal documents.
• Demonstrate flexibility in organizing work and priorities for delivering on client timelines.
• Possess excellent problem solving and decision-making skills to identify and solve issues.

Qualifications

• Ph.D. or Master’s degree in Material Science, Chemistry, Physical Organic Chemistry, Crystallography or related science field with relevant laboratory experience.
• Minimum of 5 years of related laboratory work experience in a pharmaceutical industry; or an equivalent combination of training and experience.
• Expertise in XRPD, solid form development, method development in solid-state chemistry.
• Hands on experience with analytical instrumentation, especially those used in a solid-state chemistry laboratory such as XRPD, PSD, TGA, DSC, FT-IR, Raman, KF, BET, SEM and DVS.
• Preferred Experience working in a GMP environment is a plus.
• Expertise in the interpretation of solid-state analytical data including XRPD, microscopy, spectroscopy, thermal analysis and knowledge of wet chemistry principles.
• Extensive knowledge and working experience in solid state drug development.
• Knowledge of cGMP regulations for the pharmaceutical industry.
• Excellent written and verbal communication skills.
• Strong leadership skills.