Senior Research Associate, Translational
About the role
The Senior Research Associate will be part of the Platform Group at Mirai and will support laboratory research activities towards development of novel technologies enabling next generation genomic medicines. The successful candidate will have a strong understanding of the technical and equipment needs in a lab as well as significant hands-on experience with standard and cell culturing and in vitro cell biology techniques. They will work independently and as part of a collaborative team.
Responsibilities
- Independently perform experiments related to in vivo and in vitro LNP using lab techniques that include flow cytometry, mammalian cell culture, mouse and NHP sample processing, cell isolation, ELISAs, plate-based reporter assays, cell killing assays, transfection, and protein binding assays
- Develop new in vitro bio-assays or optimize existing ones based on in-depth knowledge of laboratory techniques
- Analyze and accurately document assay results in an electronic lab notebook or other technical reporting formats
Qualifications
- M.S. or B.S. in Biology, Biochemistry, Molecular Biology, or related field with 3+ years (M.S.) or 5+ years(B.S.) of relevant experience
- Previous experience with immune cell isolation and flow cytometry characterization is required
- Comfort with handling and processing NHP & Mouse tissue samples
- Strong primary and cell line culture experience, including experience executing protocols, troubleshooting assays, and carrying out literature searches for method evaluation and refinement
- Knowledge of immunology, experience working with LNPs, and familiarity with performing BLI on octet instruments is a plus
- Proven ability to work independently and cross-functionally with highly skilled teams in a fast-paced, entrepreneurial, and technical environment
- Strong organizational and problem-solving skills
- Motivated, curious, and comfortable working with highly technical projects and personnel
- Excellent communication and presentation skills, capable of conveying technical information in a clear and thorough manner
- Comfortable delivering against challenging commitments
What we value
- Scientific rigor and attention to data quality and reproducibility
- Curiosity and a problem-solving mindset
- Ability to work both independently and collaboratively in a fast-paced environment
- Clear and concise communication across disciplines
- Ownership and accountability in driving projects forward
Location
Cambridge, MA
About Flagship Pioneering
Flagship Pioneering invents and builds platform companies, each with the potential for multiple products that transform human health, sustainability and beyond. Since its launch in 2000, Flagship has originated more than 100 companies. Many of these companies have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.
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