Senior Research Associate - Scientist I, Discovery Biology
Planet Pharma · Brisbane, CA · 3 wk ago
AnalystContract
Senior Research Associate - Scientist I, Discovery Biology The Opportunity Plan, execute, and analyze in vitro cell-based assays to support small molecule and degrader-antibody conjugate discovery efforts in cancer oncology, including mechanistic studies and new target identificationPerform routine and specialized cell culture (cancer cell lines and/or primary cells) to support lead progression and follow-up studiesIndependently troubleshoot experimental issues and proactively introduce new techniques and efficiencies to accelerate drug discoveryAnalyze and interpret experimental data to quantify drug potency and activity, and communicate results clearly to project teamsUpload and maintain experimental data in electronic lab notebooks and enterprise databases with a high level of accuracy and timelinessCollaborate closely with scientists across disciplines, contributing to experimental design, meeting presentations, and project strategy What You’ll Bring Bachelor’s degree with 8+ years of relevant industry experience, Master’s degree with 4+ years, or Ph.D. with 1–2 years of industry experience in Cell Biology, Cancer Biology, Molecular Biology, or a related field (final level based on education, experience, and demonstrated independence)Strong background in cancer cell biologyExtensive hands-on experience with cell culture (cancer cell lines and/or primary cells) and good aseptic techniqueHands-on experience and proficiency with low- to medium-throughput cell-based assay platforms such as HTRF, AlphaLISA/ELISA, CellTiter-Glo, RT-qPCR, flow cytometry, and Western blotting/JESS, and other functional assay developmentAbility to conceive, design, and execute hypothesis-testing experiments that directly contribute to project success with minimal supervisionStrong organizational skills, attention to detail, data integrity, and commitment to reproducible researchClear written and verbal communication skills and demonstrated effectiveness working with cross-functional teamsAbility to balance multiple studies and deliver high-quality results against project timelines Preferred Experience with gene editing such as CRISPR and RNA interferenceExperience with targeted protein degradation, including PROTACs, degrader-antibody-conjugates, and molecular glue degradersPrior industry drug discovery experience Location: Onsite – Brisbane, CA