Senior Research Associate, Discovery Pharmacology

Responsibilities

• Work both independently and collaboratively with the scientific manager to drive drug discovery and development projects.
• Culture and maintain mammalian cells, manage reagents and working stocks in addition to contributing to general lab maintenance.
• Design, optimize, automate, execute, and troubleshoot a range of assays, including cellular, biochemical, and complex in vitro bioassays.
• Standardize and optimize assay protocols and draft assay SOPs.
• Document assay methods, raw data, and results in an electronic laboratory notebook (ELN), ensuring reproducibility and data integrity.
• Make presentations and present data at project team meetings to support decision making.

Requirements

• BS or MS in Molecular Biology, Cell Biology, Biochemistry, Bioengineering, or a related discipline, and a minimum of 5 years of industry experience in a drug discovery and/or development setting.
• Strong expertise in technical methods in AAV gene therapy for cellular transduction assays (aseptic technique), genome titration (qPCR, ddPCR), transgene expression (RT-qPCR, ddPCR), and protein analysis (Western Blot, ELISA, and capillary electrophoresis).
• Good understanding and hands-on experience developing and performing a wide range of analytical and bioassays with fluency in data analysis and application of statistical modalities.
• Experience in state-of-art assay technologies such as MSD, HTRF, AlphaLISA, Luminex, etc.
• Hands on experience in automation instruments and platforms (e.g. Bravo, Echo, I.DOT, Digital dispenser, etc.).
• Proficient in documenting experimental design, analysis and interpretation of data in ELN.
• Excellent data presentation, oral and written communication skills.
• Detail-oriented, organized, flexible, and capable of multitasking in a fast-paced environment.

Qualifications

• Experience working across diverse therapeutic modalities, including viral based gene therapy, mRNA-LNP or other nucleic acid therapeutics, and small molecules.
• Background in the field of aging/rejuvenation biology.
• Familiarity with assay qualification criteria, processes, and SOP authoring.

Benefits

The salary range for Redwood City: Senior Research Associate: $109,200 - $140,000 Exact compensation may vary based on skills, experience, and location.

Pay

Exact compensation may vary based on skills, experience, and location.

Schedule

Not specified.

Skills

Not specified.

Benefits

Not specified.

Pay

Not specified.

Schedule

Not specified.