Senior Research Associate (Contractor)

Brisbane, California About This Opportunity: At Freenome, we are seeking a Senior Research Associate to help grow our Genomics Assay Development team. At Freenome, you will help develop the assay technologies used to analyze patient samples and contribute to our mission of early cancer detection. The ideal candidate will work to develop assay technologies for our multiomic platform manually and on robotic platforms. You will develop, characterize, verify, and validate clinical-grade assays to measure complex, blood-based analytes (e.g., whole-genome sequencing of cfDNA). You will work cross-functionally with Research & Development teams, automation and process engineering, computational science, and clinical operations to develop and transfer NGS-based assays in a regulated, high-throughput environment. You are passionate about developing life saving diagnostics using NGS technologies, and you will have a significant impact on the continued growth of an organization dedicated to changing the entire landscape of cancer. The role reports to the Manager of Genomics Late Stage Development. This role will be an onsite role based in our Brisbane, California headquarters. What You’ll Do: Apply knowledge of molecular biology, nucleic-acid biochemistry, and next-generation sequencing to develop assays for DNA, including genome-wide and targeted approachesParticipate in experimental design and independently plan and execute mission-critical experiments to optimize and characterize assay performanceCreate and manipulate high impact assay inputs, including use of biological samples and formulation of contrived samples and reagents as requiredGather high-quality data, take detailed notes, and openly communicate on lessons learned while performing experimentsPerform data analysis, create summary presentations, and present results cross-functionallyPerform technical troubleshooting, identify and implement process improvements across the lab by thinking critically about the execution of all experimentsBuild productive working relationships and collaborate with engineers and clinical laboratory members to transition development protocols into clinical production, including automation, validation experiments, and SOP developmentContribute to writing study protocols and reports. Diligently apply current Good Laboratory and Documentation Practices (cGLP, cGDP) Must Haves: Bachelor’s or Master’s degree in molecular biology, biochemistry, genetics, or a related field with at least 4 years of professional experience in the life sciences. Prior experience in clinical diagnostics and/or working in a start-up environment is preferred Experience executing verification and validation studies for IVD assays in a regulated laboratory environment (GLP)Hands-on experience in Next-gen sequencing (NGS) based assay development including extraction, library preparation, target capture, and sequencing Familiarity with molecular biology, genomics, NGS, assay development, sample preparation, reagent handling, or related laboratory workflows (e.g. plasma separation processes, DNA/RNA extraction, purification, and quantification, NGS library preparation)Experience designing, planning, and executing successful experiments, interpreting results, preparing data for review, and giving effective scientific presentationsHigh attention to detail and ability to record accurate and detailed observations, assess impact, and perform troubleshooting as requiredAbility to manually pipette with high confidence, accuracy, and precisionClear and proactive communication skills and ability to collaborate effectively with team members in the same and adjacent disciplinesStrong organizational skills and the ability to contribute the design and implementation of new processesFlexible and highly motivated to learn new skills and comfortable adapting to changing priorities Nice To Haves: Experience in working with with methylated ctDNA/cfDNA as an analyte in liquid biopsy workflows Experience with automated liquid handlers, laboratory information systems, sample tracking systems, and equipment scheduling/status toolsFamiliarity with programing in a scientific programming language (e.g., Python or R) Additional Information: Contractors may be hired through a third-party provider and will be considered contingent workers. We invite you to check out our career page @ freenome.com/job-openings/ for additional company information. Freenome is proud to be an equal opportunity employer and we value diversity. Freenome does not discriminate on the basis of race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical condition, pregnancy, genetic information, gender, sexual orientation, gender identity or expression, veteran status, or any other status protected under federal, state, or local law. Applicants have rights under Federal Employment Laws. Family & Medical Leave Act (FMLA)Equal Employment Opportunity (EEO)Employee Polygraph Protection Act (EPPA) California applicants please review the CCPA Notice at Collection here: California Consumer Privacy Act (CCPA) Create a Job Alert Interested in building your career at Freenome? Get future opportunities sent straight to your email. Create alert Apply for this job indicates a required field First Name* Last Name* Email* Phone Country* Phone* 244 results found No results found Afghanistan+93Åland Islands+358Albania+355Algeria+213American Samoa+1Andorra+376Angola+244Anguilla+1Antigua & Barbuda+1Argentina+54Armenia+374Aruba+297Ascension Island+247Australia+61Austria+43Azerbaijan+994Bahamas+1Bahrain+973Bangladesh+880Barbados+1Belarus+375Belgium+32Belize+501Benin+229Bermuda+1Bhutan+975Bolivia+591Bosnia & Herzegovina+387Botswana+267Brazil+55British Indian Ocean Territory+246British Virgin Islands+1Brunei+673Bulgaria+359Burkina Faso+226Burundi+257Cambodia+855Cameroon+237Canada+1Cape Verde+238Caribbean Netherlands+599Cayman Islands+1Central African Republic+236Chad+235Chile+56China+86Christmas Island+61Cocos (Keeling) Islands+61Colombia+57Comoros+269Congo - Brazzaville+242Congo - Kinshasa+243Cook Islands+682Costa Rica+506Côte d’Ivoire+225Croatia+385Cuba+53Curaçao+599Cyprus+357Czechia+420Denmark+45Djibouti+253Dominica+1Dominican Republic+1Ecuador+593Egypt+20El Salvador+503Equatorial Guinea+240Eritrea+291Estonia+372Eswatini+268Ethiopia+251Falkland Islands+500Faroe Islands+298Fiji+679Finland+358France+33French Guiana+594French Polynesia+689Gabon+241Gambia+220Georgia+995Germany+49Ghana+233Gibraltar+350Greece+30Greenland+299Grenada+1Guadeloupe+590Guam+1Guatemala+502Guernsey+44Guinea+224Guinea-Bissau+245Guyana+592Haiti+509Honduras+504Hong Kong SAR China+852Hungary+36Iceland+354India+91Indonesia+62Iran+98Iraq+964Ireland+353Isle of Man+44Israel+972Italy+39Jamaica+1Japan+81Jersey+44Jordan+962Kazakhstan+7Kenya+254Kiribati+686Kosovo+383Kuwait+965Kyrgyzstan+996Laos+856Latvia+371Lebanon+961Lesotho+266Liberia+231Libya+218Liechtenstein+423Lithuania+370Luxembourg+352Macao SAR China+853Madagascar+261Malawi+265Malaysia+60Maldives+960Mali+223Malta+356Marshall Islands+692Martinique+596Mauritania+222Mauritius+230Mayotte+262Mexico+52Micronesia+691Moldova+373Monaco+377Mongolia+976Montenegro+382Montserrat+1Morocco+212Mozambique+258Myanmar (Burma)+95Namibia+264Nauru+674Nepal+977Netherlands+31New Caledonia+687New Zealand+64Nicaragua+505Niger+227Nigeria+234Niue+683Norfolk Island+672North Korea+850North Macedonia+389Northern Mariana Islands+1Norway+47Oman+968Pakistan+92Palau+680Palestinian Territories+970Panama+507Papua New Guinea+675Paraguay+595Peru+51Philippines+63Poland+48Portugal+351Puerto Rico+1Qatar+974Réunion+262Romania+40Russia+7Rwanda+250Samoa+685San Marino+378São Tomé & Príncipe+239Saudi Arabia+966Senegal+221Serbia+381Seychelles+248Sierra Leone+232Singapore+65Sint Maarten+1Slovakia+421Slovenia+386Solomon Islands+677Somalia+252South Africa+27South Korea+82South Sudan+211Spain+34Sri Lanka+94St. Barthélemy+590St. Helena+290St. Kitts & Nevis+1St. Lucia+1St. Martin+590St. Pierre & Miquelon+508St. Vincent & Grenadines+1Sudan+249Suriname+597Svalbard & Jan Mayen+47Sweden+46Switzerland+41Syria+963Taiwan+886Tajikistan+992Tanzania+255Thailand+66Timor-Leste+670Togo+228Tokelau+690Tonga+676Trinidad & Tobago+1Tunisia+216Turkey+90Turkmenistan+993Turks & Caicos Islands+1Tuvalu+688U.S. Virgin Islands+1Uganda+256Ukraine+380United Arab Emirates+971United Kingdom+44United States+1Uruguay+598Uzbekistan+998Vanuatu+678Vatican City+39Venezuela+58Vietnam+84Wallis & Futuna+681Western Sahara+212Yemen+967Zambia+260Zimbabwe+263 Location (City)* Resume/CV* Attach Enter manually Accepted file types: pdf, doc, docx, txt, rtf Cover Letter Attach Enter manually Accepted file types: pdf, doc, docx, txt, rtf Describe a hands-on NGS assay you’ve worked on from sample prep through sequencing. What parts you handled, what you learned, and how your work supported assay development?* Give an example of how you generated and analyzed experimental data to troubleshoot or improve an assay. What the issue was, how you approached it, and what changed as a result?* Are you fully authorized to work in the United States without need for sponsorship now or in the future? * Select... Voluntary Self-Identification For government reporting purposes, we ask candidates to respond to the below self-identification survey. Completion of the form is entirely voluntary. Whatever your decision, it will not be considered in the hiring process or thereafter. Any information that you do provide will be recorded and maintained in a confidential file. As set forth in Freenome’s Equal Employment Opportunity policy, we do not discriminate on the basis of any protected group status under any applicable law. Gender Select... Are you Hispanic/Latino? Select... 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What You’ll Do: Apply knowledge of molecular biology, nucleic-acid biochemistry, and next-generation sequencing to develop assays for DNA, including genome-wide and targeted approachesParticipate in experimental design and independently plan and execute mission-critical experiments to optimize and characterize assay performanceCreate and manipulate high impact assay inputs, including use of biological samples and formulation of contrived samples and reagents as requiredGather high-quality data, take detailed notes, and openly communicate on lessons learned while performing experimentsPerform data analysis, create summary presentations, and present results cross-functionallyPerform technical troubleshooting, identify and implement process improvements across the lab by thinking critically about the execution of all experimentsBuild productive working relationships and collaborate with engineers and clinical laboratory members to transition development protocols into clinical production, including automation, validation experiments, and SOP developmentContribute to writing study protocols and reports. Diligently apply current Good Laboratory and Documentation Practices (cGLP, cGDP) Must Haves: Bachelor’s or Master’s degree in molecular biology, biochemistry, genetics, or a related field with at least 4 years of professional experience in the life sciences. Prior experience in clinical diagnostics and/or working in a start-up environment is preferred Experience executing verification and validation studies for IVD assays in a regulated laboratory environment (GLP)Hands-on experience in Next-gen sequencing (NGS) based assay development including extraction, library preparation, target capture, and sequencing Familiarity with molecular biology, genomics, NGS, assay development, sample preparation, reagent handling, or related laboratory workflows (e.g. plasma separation processes, DNA/RNA extraction, purification, and quantification, NGS library preparation)Experience designing, planning, and executing successful experiments, interpreting results, preparing data for review, and giving effective scientific presentationsHigh attention to detail and ability to record accurate and detailed observations, assess impact, and perform troubleshooting as requiredAbility to manually pipette with high confidence, accuracy, and precisionClear and proactive communication skills and ability to collaborate effectively with team members in the same and adjacent disciplinesStrong organizational skills and the ability to contribute the design and implementation of new processesFlexible and highly motivated to learn new skills and comfortable adapting to changing priorities Nice To Haves: Experience in working with with methylated ctDNA/cfDNA as an analyte in liquid biopsy workflows Experience with automated liquid handlers, laboratory information systems, sample tracking systems, and equipment scheduling/status toolsFamiliarity with programing in a scientific programming language (e.g., Python or R) Additional Information: Contractors may be hired through a third-party provider and will be considered contingent workers. We invite you to check out our career page @ freenome.com/job-openings/ for additional company information. Freenome is proud to be an equal opportunity employer and we value diversity. Freenome does not discriminate on the basis of race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical condition, pregnancy, genetic information, gender, sexual orientation, gender identity or expression, veteran status, or any other status protected under federal, state, or local law. Applicants have rights under Federal Employment Laws. Family & Medical Leave Act (FMLA)Equal Employment Opportunity (EEO)Employee Polygraph Protection Act (EPPA) California applicants please review the CCPA Notice at Collection here: California Consumer Privacy Act (CCPA) 244 results found No results found Afghanistan+93Åland Islands+358Albania+355Algeria+213American Samoa+1Andorra+376Angola+244Anguilla+1Antigua & Barbuda+1Argentina+54Armenia+374Aruba+297Ascension Island+247Australia+61Austria+43Azerbaijan+994Bahamas+1Bahrain+973Bangladesh+880Barbados+1Belarus+375Belgium+32Belize+501Benin+229Bermuda+1Bhutan+975Bolivia+591Bosnia & Herzegovina+387Botswana+267Brazil+55British Indian Ocean Territory+246British Virgin Islands+1Brunei+673Bulgaria+359Burkina Faso+226Burundi+257Cambodia+855Cameroon+237Canada+1Cape Verde+238Caribbean Netherlands+599Cayman Islands+1Central African Republic+236Chad+235Chile+56China+86Christmas Island+61Cocos (Keeling) Islands+61Colombia+57Comoros+269Congo - Brazzaville+242Congo - Kinshasa+243Cook Islands+682Costa Rica+506Côte d’Ivoire+225Croatia+385Cuba+53Curaçao+599Cyprus+357Czechia+420Denmark+45Djibouti+253Dominica+1Dominican Republic+1Ecuador+593Egypt+20El Salvador+503Equatorial Guinea+240Eritrea+291Estonia+372Eswatini+268Ethiopia+251Falkland Islands+500Faroe Islands+298Fiji+679Finland+358France+33French Guiana+594French Polynesia+689Gabon+241Gambia+220Georgia+995Germany+49Ghana+233Gibraltar+350Greece+30Greenland+299Grenada+1Guadeloupe+590Guam+1Guatemala+502Guernsey+44Guinea+224Guinea-Bissau+245Guyana+592Haiti+509Honduras+504Hong Kong SAR China+852Hungary+36Iceland+354India+91Indonesia+62Iran+98Iraq+964Ireland+353Isle of Man+44Israel+972Italy+39Jamaica+1Japan+81Jersey+44Jordan+962Kazakhstan+7Kenya+254Kiribati+686Kosovo+383Kuwait+965Kyrgyzstan+996Laos+856Latvia+371Lebanon+961Lesotho+266Liberia+231Libya+218Liechtenstein+423Lithuania+370Luxembourg+352Macao SAR China+853Madagascar+261Malawi+265Malaysia+60Maldives+960Mali+223Malta+356Marshall Islands+692Martinique+596Mauritania+222Mauritius+230Mayotte+262Mexico+52Micronesia+691Moldova+373Monaco+377Mongolia+976Montenegro+382Montserrat+1Morocco+212Mozambique+258Myanmar (Burma)+95Namibia+264Nauru+674Nepal+977Netherlands+31New Caledonia+687New Zealand+64Nicaragua+505Niger+227Nigeria+234Niue+683Norfolk Island+672North Korea+850North Macedonia+389Northern Mariana Islands+1Norway+47Oman+968Pakistan+92Palau+680Palestinian Territories+970Panama+507Papua New Guinea+675Paraguay+595Peru+51Philippines+63Poland+48Portugal+351Puerto Rico+1Qatar+974Réunion+262Romania+40Russia+7Rwanda+250Samoa+685San Marino+378São Tomé & Príncipe+239Saudi Arabia+966Senegal+221Serbia+381Seychelles+248Sierra Leone+232Singapore+65Sint Maarten+1Slovakia+421Slovenia+386Solomon Islands+677Somalia+252South Africa+27South Korea+82South Sudan+211Spain+34Sri Lanka+94St. Barthélemy+590St. Helena+290St. Kitts & Nevis+1St. Lucia+1St. Martin+590St. Pierre & Miquelon+508St. Vincent & Grenadines+1Sudan+249Suriname+597Svalbard & Jan Mayen+47Sweden+46Switzerland+41Syria+963Taiwan+886Tajikistan+992Tanzania+255Thailand+66Timor-Leste+670Togo+228Tokelau+690Tonga+676Trinidad & Tobago+1Tunisia+216Turkey+90Turkmenistan+993Turks & Caicos Islands+1Tuvalu+688U.S. Virgin Islands+1Uganda+256Ukraine+380United Arab Emirates+971United Kingdom+44United States+1Uruguay+598Uzbekistan+998Vanuatu+678Vatican City+39Venezuela+58Vietnam+84Wallis & Futuna+681Western Sahara+212Yemen+967Zambia+260Zimbabwe+263