Jobs · Analyst · California

Senior Research Associate

CHEManager International · San Francisco, CA · 3 days ago
Analyst$109k–$140k/yrFull-time

Key Responsibilities

  • Independently maintain, expand, characterize, and troubleshoot a broad range of mammalian cell culture systems, including immortalized and primary cell models.
  • Design and execute molecular biology workflows including cloning, plasmid construction, nucleic acid preparation, and mRNA design/synthesis.
  • Produce, optimize, and deploy viral delivery systems (including lentiviral and AAV platforms) and non-viral systems (LNPs) for gene perturbation, expression, and cellular engineering studies.
  • Perform CRISPR-based genome editing, pooled or arrayed perturbation workflows, and follow-up validation experiments.
  • Develop, optimize, and execute robust cell-based assays, reporter systems, and phenotypic readouts.
  • Maintain exemplary documentation practices in ELN systems and help establish scalable SOPs and laboratory best practices.
  • Demonstrate high productivity and ability to complete work in a timely manner.

Who You Are

  • BS or MS in Molecular Biology, Cell Biology, Biochemistry, Bioengineering, or a related discipline.
  • 2+ years of relevant hands-on experience in biotech, pharma, or leading academic laboratories.
  • Proven strength in mammalian cell culture and execution of complex bench workflows with high reproducibility.
  • Strong molecular biology experience, including cloning and nucleic acid-based assays.
  • Demonstrated experience with viral transduction, gene delivery, and/or genome editing platforms.
  • Ability to independently troubleshoot experiments, manage multiple priorities, and deliver high-quality work with speed and precision.
  • Excellent organizational skills, clear communication, and strong ownership mentality.

Preferred Qualifications

  • Experience with primary human cells, stem cell systems, organoids, ex vivo platforms or other advanced cellular models.
  • Experience with functional genomics approaches such as CRISPR screens, Perturb-seq, or high-throughput perturbation platforms.
  • Experience with single-cell and spatial omics platforms, including single-cell RNA-seq, single-nucleus RNA-seq, spatial transcriptomics, or related workflows.
  • Experience synthesizing mRNA and corresponding delivery platforms.
  • Experience with flow cytometry, imaging, high-content screening, or automated cell analysis.
  • Strong interest in aging biology, regenerative medicine, or mechanisms of cellular rejuvenation.
  • Hands-on experience with ex vivo culture systems.

Pay

The Salary Range For Redwood City Senior Research Associate: $109,200 - $140,000 Exact compensation may vary based on skills, experience, and location.

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