Senior Research Associate
CHEManager International · San Francisco, CA · 3 days ago
Analyst$109k–$140k/yrFull-time
Key Responsibilities
- Independently maintain, expand, characterize, and troubleshoot a broad range of mammalian cell culture systems, including immortalized and primary cell models.
- Design and execute molecular biology workflows including cloning, plasmid construction, nucleic acid preparation, and mRNA design/synthesis.
- Produce, optimize, and deploy viral delivery systems (including lentiviral and AAV platforms) and non-viral systems (LNPs) for gene perturbation, expression, and cellular engineering studies.
- Perform CRISPR-based genome editing, pooled or arrayed perturbation workflows, and follow-up validation experiments.
- Develop, optimize, and execute robust cell-based assays, reporter systems, and phenotypic readouts.
- Maintain exemplary documentation practices in ELN systems and help establish scalable SOPs and laboratory best practices.
- Demonstrate high productivity and ability to complete work in a timely manner.
Who You Are
- BS or MS in Molecular Biology, Cell Biology, Biochemistry, Bioengineering, or a related discipline.
- 2+ years of relevant hands-on experience in biotech, pharma, or leading academic laboratories.
- Proven strength in mammalian cell culture and execution of complex bench workflows with high reproducibility.
- Strong molecular biology experience, including cloning and nucleic acid-based assays.
- Demonstrated experience with viral transduction, gene delivery, and/or genome editing platforms.
- Ability to independently troubleshoot experiments, manage multiple priorities, and deliver high-quality work with speed and precision.
- Excellent organizational skills, clear communication, and strong ownership mentality.
Preferred Qualifications
- Experience with primary human cells, stem cell systems, organoids, ex vivo platforms or other advanced cellular models.
- Experience with functional genomics approaches such as CRISPR screens, Perturb-seq, or high-throughput perturbation platforms.
- Experience with single-cell and spatial omics platforms, including single-cell RNA-seq, single-nucleus RNA-seq, spatial transcriptomics, or related workflows.
- Experience synthesizing mRNA and corresponding delivery platforms.
- Experience with flow cytometry, imaging, high-content screening, or automated cell analysis.
- Strong interest in aging biology, regenerative medicine, or mechanisms of cellular rejuvenation.
- Hands-on experience with ex vivo culture systems.
Pay
The Salary Range For Redwood City Senior Research Associate: $109,200 - $140,000 Exact compensation may vary based on skills, experience, and location.