Senior Process Engineer / SME – Chromatography Systems

Key Responsibilities

• Serve as technical SME for chromatography systems and purification equipment.
• Support startup, commissioning, qualification, and operational readiness.
• Provide vendor oversight and challenge technical solutions when required.
• Troubleshoot equipment and process issues.
• Support equipment acceptance and performance verification activities.
• Review vendor documentation and design deliverables.
• Support cross-functional teams during project execution.

Technical Areas of Expertise

• Simulated Moving Bed (SMB) Chromatography
• Continuous Chromatography
• High-Pressure Chromatography Systems
• Resin Management
• Resin Qualification
• Column Packing and Unpacking
• Buffer Systems
• Buffer Preparation
• Column Operations
• Purification System Troubleshooting

Required Qualifications

• BS in Chemical Engineering, Biochemical Engineering, Biotechnology, or related field.
• 8+ years of chromatography or downstream processing experience.
• Extensive experience with:
• Chromatography systems
• Resin handling
• Column packing
• Buffer preparation
• Strong understanding of purification equipment and mechanical systems.
• Experience managing equipment vendors and suppliers.

Preferred Qualifications

• SMB chromatography experience.
• Protein purification experience.
• mAb, plasma, biologics, nutraceutical, or protein processing experience.
• Experience with Cytiva, Pall, Novasep, or equivalent chromatography platforms.