Jobs · OTHR · Massachusetts

Senior/Principal Machine Learning Researcher - Biological Foundational Models

Cellular Intelligence · Boston, MA · 1 mo ago
On-siteOTHR$180k–$275k/yrFull-time

About the role

As a Senior Machine Learning Researcher - Biological Foundational Models, you will play a key role in developing foundational models for single-cell RNA sequencing data. Working closely with other machine learning researchers and computational biologists, you’ll design cutting-edge AI solutions, contribute to pioneering research, and help build the core infrastructure driving Cellular Intelligence’s cell-replacement therapy platform. This role is ideal for a machine learning expert driven by scientific inquiry and eager to pioneer biological discoveries through foundational AI models.

Responsibilities

  • Design, train, and optimize foundational models for single-cell RNA sequencing and other high-dimensional omics data
  • Collaborate closely with computational biologists to ensure models produce biologically meaningful, interpretable outputs, engaging deeply with biological questions and research
  • Design and implement novel deep learning architectures, including transformer-based models tailored to biological data
  • Build scalable, distributed pipelines for training and inference across trillion-token biological datasets
  • Provide mentorship and technical guidance to other machine learning researchers on the team

Qualifications

  • 6+ years of experience in machine learning, transformer-based deep learning, and large-scale data analysis, preferably in biological applications
  • Master’s degree or higher in Computer Science, Artificial Intelligence, Computational Biology, or a related field
  • Strong proficiency in Python and deep learning frameworks such as PyTorch or TensorFlow
  • Proven experience building and optimizing large-scale models, including transformer-based architectures
  • Demonstrated track record of independent research and end-to-end model development, from prototyping to production
  • Passion for AI-driven biology and its potential to transform healthcare

Preferred Qualifications

  • Strongly preferred: PhD with a strong publication record in top machine learning and/or computational biology journals
  • Strongly preferred: Extensive background in biological research and biological modeling, ideally with single-cell RNA sequencing data
  • Experience with reinforcement learning (e.g., RLHF, PPO), diffusion models, or multi-modal architectures applied to structured, high-dimensional data
  • Experience in startups or fast-paced environments, with a self-directed, proactive work style

Benefits

  • Take a technical leadership role with a mission-driven company with the potential to significantly impact the lives of millions
  • Work alongside a talented and passionate team at the forefront of AI and cellular biology
  • Contribute to the development of groundbreaking therapies that address significant unmet medical needs
  • Enjoy a competitive salary and benefits package, including flexible work options

Compensation Range

$180K - $275K

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