Senior Principal Enterprise Architect

Description

Penn Medicine is dedicated to its tripartite mission of providing the highest quality of care to patients, conducting innovative research, and educating future leaders in the field of medicine. Working for this leading academic medical center means collaborating with top clinical, technical, and business professionals across all disciplines.

About the Role

The Senior Principal Enterprise Architect – Enterprise Strategy & Transformation serves as a foundational enterprise architecture leader responsible for establishing, scaling, and maturing the Enterprise Architecture (EA) function across Penn Medicine's clinical, research, academic, and administrative domains.

Responsibilities

• Develops and maintains the enterprise architecture operating model, including governance frameworks, standards libraries, decision rights, roles and responsibilities, and engagement models that enable consistent, enterprise-wide architectural coherence.
• Develops multi-year enterprise architecture blueprints aligned to Penn Medicine’s strategic plan, encompassing clinical, research, academic, and administrative technology domains, and presents findings and recommendations to C-suite and executive leadership.
• Translates enterprise and business strategy into actionable architecture direction, working with executive and operational leadership to define the Business Capability Model, identify capability gaps, and align technology investments to strategic priorities across Penn Medicine’s integrated missions.
• Defines, evolves, and enforces the enterprise architecture taxonomy, metamodel, and artifact standards, ensuring consistency and usability of EA artifacts across domains and stakeholder audiences.
• Co-leads the Architecture Review Board (ARB), establishing ARB charter, review criteria, escalation pathways, and decision frameworks that govern architectural decisions across the enterprise portfolio.
• Leads the assessment, requirements definition, vendor evaluation, and selection of the enterprise EA repository and tooling platform, including defining the taxonomy, metamodel, and usage standards for EA artifact management.
• Defines and drives the enterprise AI and generative AI architectural strategy, including reference architectures for embedded AI, large language models (LLMs), retrieval-augmented generation (RAG), and responsible AI governance frameworks.
• Develops and maintains the Business Capability Model, enterprise application portfolio inventory, and technology investment rationalization frameworks that inform strategic planning and capital prioritization decisions.
• Governs enterprise technical debt identification, prioritization, and remediation roadmaps, partnering with delivery and operations leaders to ensure systematic reduction of architectural risk across the technology portfolio.
• Mentors and upskills Principal, Domain, and Solution Architects across the organization, advancing architectural thinking, standards adoption, and governance participation at all levels of the architecture practice.
• Partners with the DTS leadership, and clinical, operational, and research leadership to advise on strategic architecture decisions, technology investment trade-offs, and long-range platform direction.
• Produces executive architecture briefings, strategy documents, and board-level presentations that communicate enterprise architecture direction, portfolio health, and strategic technology recommendations in terms accessible to non-technical leadership.
• Flexes to lead or support any strategic initiative, program, or architecture assessment assigned to the EA backlog by the Vice President, Enterprise Architecture, Research & Strategy, providing domain-agnostic architectural leadership as organizational priorities evolve.
• Maintains awareness of current and emerging technology trends across the healthcare, research, and enterprise technology landscape. Evaluates strategic and architectural implications and communicates findings to executive leadership to inform long-term technology investment decisions.
• Leads technology scenario planning to anticipate future business, regulatory, and technology changes; incorporates flexibility and resilience into enterprise architecture roadmaps to reduce lock-in and improve adaptability.

Credentials

Enterprise Architecture TOGAF Certification is preferred.

Qualifications

• Bachelor's Degree is required. Education Specialization: Computer Science, Computer Engineering, Information Systems, or related field.
• 15+ years of experience in Information Technology, Computer Science, Information Systems, or a related field, with 10+ years in Enterprise Architecture and demonstrated experience in enterprise-scale healthcare, academic medical center, or highly regulated industry environments is required.
• 5+ years Enterprise Architecture experience, with demonstrated delivery of EA operating models, governance frameworks, ARB leadership, and multi-year architecture blueprints at enterprise scale is required.