Senior MSL - West(Multiple Territories)
Definium Therapeutics is a late-stage clinical biopharmaceutical company dedicated to forging a new era of psychiatry by applying scientific rigor to psychedelics. Our goal is to develop accessible treatments that unlock healing at scale. Our lead product candidate, lysergide tartrate (a proprietary orally disintegrating tablet form of lysergide (LSD) D-tartrate), represents a highly differentiated, potential best-in-class opportunity for patients suffering from generalized anxiety, major depressive disorder, and posttraumatic stress disorder. Our early-stage pipeline includes DT402, the R-enantiomer of MDMA, under development to target core symptoms of autism spectrum disorder (ASD), specifically addressing social communication challenges. Guided by the recognition that patients deserve more than better, Definium is advancing a new generation of therapeutics to address the underlying causes of psychiatric and neurological disorders. Headquartered in New York, Definium Therapeutics trades on Nasdaq under the symbol DFTX.
About the role
The Senior Medical Science Liaison (MSL) will serve as a field-based scientific and clinical expert for our psychiatry portfolio, building and maintaining strong relationships with Key Opinion Leaders (KOLs), healthcare providers, policy influencers, and other stakeholders. This role focuses on engaging the medical community to communicate scientific data, provide clinical insights, and ensure our research and development efforts align with real-world practice needs. Additionally, this role will help shape internal resources, training, and capabilities for the broader Field Medical Function.
Responsibilities
Medical Affairs & Scientific Engagement
- Identify, develop, and maintain trusted relationships with KOLs, clinical investigators, and key stakeholders across academic and clinical psychiatry.
- Serve as the primary medical resource in the field, delivering accurate and balanced scientific information about our programs to facilitate high-quality scientific exchange.
- Support scientific education at national and regional psychiatry conferences, advisory boards, and educational events.
- Gather and communicate field insights to internal stakeholders to inform strategy and decision-making.
- Provide clinical and scientific input to cross-functional teams, including R&D, Clinical Development, and Commercial.
- Respond to unsolicited requests for medical information from healthcare professionals.
- Monitor and report on the competitor landscape.
- Support clinical teams with clinical trial site identification and enrollment initiatives.
- Support investigator-initiated trial (IIT) and Phase IV trial activities as needed.
- Ensure all interactions are conducted in accordance with company policies, regulatory guidelines, and compliance requirements.
Government Affairs, Advocacy, and HEOR
- Serve as the point person for Government Affairs and HEOR to provide scientific and clinical expertise in policy discussions, public comment submissions, and stakeholder briefings.
- Support Government Affairs and Patient Advocacy in identifying and maintaining relationships with relevant government agencies, policymakers, and advocacy groups in mental health and psychiatry.
- Oversee the creation of specific slide decks and training materials for state and federal government policymakers.
- Collaborate with internal teams to develop educational materials for HEOR and advocacy organizations.
- Represent the company at government affairs forums, mental health advocacy events, and policy-related conferences as requested.
Medical Affairs Infrastructure & Capability Building
- Partner with leadership to develop core training programs for future MSL onboarding, disease state fluency, and scientific platform mastery.
- Contribute to the design of field materials, medical decks, and engagement resources (e.g., CRM design).
- Assist in establishing best practices for field insights capture, CRM documentation, and KOL engagement.
Qualifications
- Advanced scientific degree (PharmD, PhD, MD, or equivalent) strongly preferred.
- Minimum of 5+ years of MSL or related medical affairs experience; psychiatry/CNS experience required.
- Record of successfully supporting pre-launch through launch staged companies with an entrepreneurial mindset.
- Experience engaging with policy, government affairs, or advocacy stakeholders in the healthcare sector strongly preferred.
- Deep understanding of psychiatric disease states, treatment paradigms, and the U.S. healthcare landscape.
- Strong presentation, communication, and interpersonal skills.
- Ability to interpret and present complex scientific data in a clear and concise manner.
- Familiarity with CRM systems, insight tools, and compliant field operations.
- Comfortable working in a high-growth, fast-paced biotech environment with cross-functional collaboration.
- Willingness to travel up to 60% as needed.
Pay
The starting base pay range for this position is $225,560.00 - $255,000.00. Compensation will be determined based on skill set, years of experience, and geographic location. Employees in this role may be entitled to additional compensation, including bonus and equity.
Benefits
- 100% paid health benefits including Medical, Dental, and Vision for you and your dependents.
- 401(k) program with company match and vesting after the first month of employment.
- Flexible time off.
- Generous parental leave.
- Additional fun fringe perks.