Senior Microfluidic & Mechanical Design Engineer (POC Diagnostic Platform)

Key Responsibilities

• Design and optimize cartridge-based microfluidic systems.
• Develop and refine flow paths, reaction chambers, and optical interface regions.
• Address bubble control, sealing integrity, dead volume reduction, and fluid reliability.
• Support injection-molded microfluidic component design and tooling.
• Implement bonding processes such as ultrasonic welding and thermal sealing.
• Design and optimize sample loading and metering mechanisms.
• Develop solutions for capillary flow, mixing, contamination control, and fluid stability.
• Validate robustness of sample handling under environmental variation.
• Ensure repeatability and manufacturability of sample interface systems.
• Lead structural design of compact diagnostic instruments.
• Perform tolerance stack-up analysis for precision alignment.
• Design mechanical interfaces between disposable cartridge and instrument.
• Develop thermal management structures supporting precision temperature control.
• Ensure mechanical durability under transport and field use conditions.
• Support design-for-manufacturing (DFM) and production scale-up.
• Collaborate with overseas manufacturing teams on design transfer.
• Generate mechanical documentation within ISO 13485 design control framework.
• Participate in risk analysis and verification activities.

Qualifications

• Bachelor’s or Master’s degree in Mechanical Engineering, Biomedical Engineering, or related field.
• 5+ years experience in microfluidic device (Lab on a Disc preferred) or cartridge-based system development.
• Experience in sample handling and fluid management system design.
• Experience with injection-molded components and tooling.
• Strong understanding of sealing, bonding, and fluid path reliability.
• Proficiency in CAD (SolidWorks or equivalent).
• Experience in precision mechanical system design.
• Preferred: Experience in IVD or diagnostic instrumentation.
• Experience in centrifuge-based microfluidics (centrifugal microfluidics / Lab-on-a-Disc), including sample metering, separation, washing, mixing, and reagent handling on disposable cartridges/discs; ability to translate assay workflows into robust fluidic sequences.
• Experience with ultrasonic welding or thermal bonding processes.
• Experience transferring products to manufacturing.
• Familiarity with ISO 13485 design control requirements.
• Experience working with cross-border manufacturing teams.

Compensation & Benefits

• Competitive salary based on experience.
• 401(k) retirement plan.
• Health insurance.
• Paid time off.