Senior Manager, Tax

Quanterix is a global leader in ultra-sensitive biomarker detection, enabling breakthroughs in disease research, diagnostics, and drug development. Its vision is to lead the next era of precision biomarker science to power earlier detection, better decisions, and improved human health. Its mission is to make biology measurable at its most fundamental level, delivering earlier insight when it matters most. Across discovery to clinical applications, Quanterix empowers scientists and healthcare providers to improve patients’ lives through detection and understanding of disease. Its proprietary Simoa® technology delivers industry-leading sensitivity, allowing researchers to detect and quantify biomarkers in blood and other fluids at concentrations far below traditional limits. With more than 3,400 peer-reviewed publications, Quanterix has been a trusted partner to the scientific community for nearly two decades. In 2025, Quanterix acquired Akoya Biosciences, adding multiplexed tissue imaging with single-cell resolution to its portfolio. Together, the combined company offers a uniquely integrated platform that connects biology across blood and tissue—advancing precision medicine from discovery to diagnostics.

About the role

We are looking for an experienced, hands-on Tax Manager to serve as our tax leader. Reporting to the VP, Corporate Controller, this role is responsible for core domestic and international tax operations, including income tax compliance, indirect tax compliance, tax accounting, and related SOX controls for a growing global public company. You will partner closely with Accounting, SEC Reporting, Treasury, Legal, FP&A, Operations, and external advisors to support timely compliance, accurate reporting, scalable processes, and business-informed tax decisions. The successful candidate is a self-starter who can take ownership of recurring tax processes and provide clear tax insights to accounting and finance leadership.

Responsibilities

• Manage the Company’s global income tax compliance processes, including U.S. federal, state, local, and international tax filings, ensuring timely, accurate, and well-supported submissions across all jurisdictions.
• Oversee quarterly and annual tax accounting and reporting under ASC 740, including review of tax provisions, effective tax rate analyses, deferred tax assets and liabilities, uncertain tax positions, and related SEC reporting disclosures.
• Review and coordinate state and local tax filings, including income, franchise, gross receipts, sales and use, property, and other indirect tax returns, ensuring timely compliance and appropriate support across relevant jurisdictions.
• Manage VAT/GST compliance across applicable jurisdictions, including review of periodic VAT returns, supporting reconciliations, payments, refund claims, and related indirect tax filings.
• Support global transfer pricing processes, including intercompany agreements, documentation, operational compliance, and coordination with external advisors.
• Lead Article 23 import VAT reporting and related indirect tax compliance processes, including coordination with logistics, customs brokers, finance, and external advisors to ensure accurate reporting, documentation, and reconciliation of import VAT positions.
• Coordinate R&D tax credit studies, Section 382 analyses, and similar work with external third-party tax advisors.
• Maintain strong tax governance, SOX controls, process documentation, and audit-ready support for tax accounting, compliance, and reporting activities in a publicly traded company environment.
• Support tax audits and inquiries, including preparation of responses to taxing authorities, coordination with external auditors and advisors, and development of clear, well-supported technical analyses.
• Manage and coordinate third-party tax advisors, including scope, deliverables, timelines, and budgets.
• Prepare and review technical tax memoranda, position papers, return-to-provision analyses, and other documentation for management, auditors, and external advisors.
• Communicate complex tax matters clearly and effectively to finance leadership and cross-functional stakeholders.
• Evaluate SALT nexus, apportionment, filing positions, credits, incentives, and exposure areas, partnering with external advisors to support compliant and efficient state and local tax reporting.
• Develop, maintain, and periodically refresh product and service taxability matrices for sales and use tax, VAT, GST, and other indirect tax purposes, ensuring accurate tax treatment across jurisdictions, customer types, and transaction categories.
• Partner with Commercial, Legal, Operations, Billing, and IT teams to operationalize taxability determinations in ERP, billing, and order-to-cash systems, supporting accurate tax calculation, exemption certificate management, and customer invoicing.
• Identify opportunities to improve tax processes, controls, documentation, and use of systems or data to support scalable, efficient tax operations.

Requirements

• Bachelor’s degree in Accounting, Tax, Finance, or a related field.
• 8+ years of progressive corporate tax experience, including public accounting and/or corporate tax experience in a multinational environment.

Preferred Qualifications

• CPA license and/or Master’s degree in Taxation.
• Tax experience in life sciences, biotechnology, diagnostics, or medical technology.
• 4+ years of experience in corporate tax for SEC clients at public accounting or tax advisory firms.
• Strong knowledge of domestic and international tax rules, SALT matters, transfer pricing, tax planning, and tax accounting; experience with Section 382 analyses, R&D credit studies, Article 23 import VAT reporting, or similar specialized matters is a plus.
• Demonstrated analytical, research, and communication capabilities; able to form well-supported tax positions, explain them to leadership, and document them clearly.
• Experience supporting tax compliance and reporting requirements for a publicly traded company, including internal controls, SOX documentation, audit support, and SEC reporting deliverables.
• Demonstrated ability to manage external tax advisors, coordinate deliverables, review technical work product, and meet recurring compliance and reporting deadlines.
• Experience with ERP systems, tax provision or compliance software, indirect tax tools, and advanced Excel-based analysis.

Skills

• Unwavering integrity and a high bar for quality in decision-making, execution, and relationships.
• Strong tax accounting, research, and reporting skills, with the ability to translate complex issues into practical recommendations.
• Proven ability to operate independently, be hands-on, take ownership of complex workstreams, and make sound judgments in ambiguous and fast-paced situations.
• Exceptional written and verbal communication skills, with the ability to clearly document and present tax matters.
• Courage to challenge assumptions, provide counsel to finance leadership, and ask the questions that need to be asked.
• Commitment to staying current on relevant tax developments.

Schedule

This role is based in Billerica, MA (hybrid). Hybrid employees are expected to work three days per week from our Billerica, MA office, with flexibility on specific days based on business needs and personal commitments.

Benefits

• Competitive compensation and a 401k plan with employer match.
• Competitive health, dental, and vision benefits for employees and their dependents.
• Unlimited vacation policy for all exempt employees, and a generous PTO policy for non-exempt employees.
• All employees are eligible for equity, employee stock purchase plan, a performance bonus, and 1:1 financial counseling/planning.
• Tuition Assistance.
• Free, state-of-the-art onsite fitness center for all employees.
• Free snacks and drinks every day for onsite employees.