Senior Manager Manufacturing Production Process Owners

About the role

Join Amgens Mission of Serving Patients At Amgen, if you feel like you're part of something bigger, it's because you are. Our shared mission to serve patients living with serious illnesses drives all that we do. Since 1980, we've helped pioneer the world of biotech in our fight against the world's toughest diseases. With our focus on four therapeutic areas Oncology, Inflammation, General Medicine, and Rare Disease, we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you'll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller, happier lives. Our award-winning culture is collaborative, innovative, and science-based. If you have a passion for challenges and the opportunities that lie within them, you'll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Responsibilities

• Lead, coach, mentor, and develop the manufacturing process owners within the manufacturing organization.
• Foster a culture of collaboration, continuous improvement, accountability, and high performance across the team.
• Provide guidance, performance feedback, and support for career development plans for direct reports.
• Set clear priorities, define role clarity, and establish coverage plans so the PPO team can flex across site needs, emerging issues, and evolving operational demands.
• Ensure strong collaboration and coordination between Manufacturing and key partners such as Quality, Facilities and Engineering, Automation, Supply Chain, Maintenance, and other site functions.
• Manage and improve manufacturing processes to increase productivity, reduce waste, and maintain product quality and compliance.
• Strengthen process discipline, documentation quality, and operational readiness across site processes.
• Serve as an escalation point for complex execution topics, ensuring issues are evaluated, decisions are made with the right stakeholders, and actions are closed with discipline.
• Ensure manufacturing activities are performed in compliance with cGMP and all applicable regulatory requirements and internal quality standards.
• Support inspection and audit readiness by ensuring appropriate documentation, escalation pathways, and governance transparency.
• Support site teams that own compliance-critical programs, including aseptic compliance and validation-related execution, by helping prioritize resources and drive timely resolution of issues.
• Ensure disciplined execution and timely closure of quality actions, CAPAs, and effectiveness verification activities in partnership with Quality and subject matter experts.
• Support and reinforce a strong safety culture and a safe working environment for all employees.
• Provide oversight and drive process improvement initiatives aimed at increasing efficiency, improving reliability, reducing costs, and enhancing the drug product manufacturing process.
• Use lean manufacturing and other continuous improvement tools to identify opportunities and optimize operations.
• Analyze operational and quality data to identify trends, solve complex problems, and implement corrective actions.
• Collaborate and cross-functional communication with site stakeholders to ensure readiness for new processes, new products, and major operational changes.
• Support risk identification, issue resolution, and execution readiness across impacted functions and unit operations.
• Facilitate, or ensure strong facilitation of, key site governance forums used to align priorities, remove barriers, and drive execution.
• Support the site project governance operating model, including plant project prioritization, by driving disciplined intake, prioritization, execution tracking, and escalation when needed.
• Act as a point of contact for process owners during troubleshooting and resolution of manufacturing-related issues.
• Stay current on technological advancements and assess opportunities for adoption in the plant.
• Support introduction and scale-up of new technologies, equipment, and systems that enhance production capabilities and improve operational performance.
• Partner cross-functionally to ensure technology-related changes are effectively planned, implemented, and sustained.

Qualifications

• Bachelor's degree in Life Sciences, Physical Sciences, Engineering, or a related technical discipline and 8+ years of Manufacturing and Operations experience.
• Doctorate degree and 2 years of Manufacturing and Operations experience.
• Masters degree and 6 years of Manufacturing and Operations experience.
• Bachelors degree and 8 years of Manufacturing and Operations experience.
• Associates degree and 10 years of Manufacturing and Operations experience.
• High school diploma/GED and 12 years of Manufacturing and Operations experience.
• Minimum of 2 years experience directly managing people and/or leadership experience leading teams, projects, programs, or directing the allocation or resources.
• Basic Qualifications: Doctorate degree and 2 years of Manufacturing and Operations experience OR Masters degree and 6 years of Manufacturing and Operations experience OR Bachelors degree and 8 years of Manufacturing and Operations experience OR Associates degree and 10 years of Manufacturing and Operations experience OR High school diploma/GED and 12 years of Manufacturing and Operations experience OR Basic Qualifications: Doctorate degree and 2 years of Manufacturing and Operations experience OR Masters degree and 6 years of Manufacturing and Operations experience OR Bachelors degree and 8 years of Manufacturing and Operations experience OR Associates degree and 10 years of Manufacturing and Operations experience OR High school diploma/GED and 12 years of Manufacturing and Operations experience OR Basic Qualifications: Doctorate degree and 2 years of Manufacturing and Operations experience OR Masters degree and 6 years of Manufacturing and Operations experience OR Bachelors degree and 8 years of Manufacturing and Operations experience OR Associates degree and 10 years of Manufacturing and Operations experience OR High school diploma/GED and 12 years of Manufacturing and Operations experience OR Basic Qualifications: Doctorate degree and 2 years of Manufacturing and Operations experience OR Masters degree and 6 years of Manufacturing and Operations experience OR Bachelors degree and 8 years of Manufacturing and Operations experience OR Associates degree and 10 years of Manufacturing and Operations experience OR High school diploma/GED and 12 years of Manufacturing and Operations experience OR Basic Qualifications: Doctorate degree and 2 years of Manufacturing and Operations experience OR Masters degree and 6 years of Manufacturing and Operations experience OR Bachelors degree and 8 years of Manufacturing and Operations experience OR Associates degree and 10 years of Manufacturing and Operations experience OR High school diploma/GED and 12 years of Manufacturing and Operations experience OR Basic Qualifications: Doctorate degree and 2 years of Manufacturing and Operations experience OR Masters degree and 6 years of Manufacturing and Operations experience OR Bachelors degree and 8 years of Manufacturing and Operations experience OR Associates degree and 10 years of Manufacturing and Operations experience OR High school diploma/GED and 12 years of Manufacturing and Operations experience OR Basic Qualifications: Doctorate degree and 2 years of Manufacturing and Operations experience OR Masters degree and 6 years of Manufacturing and Operations experience OR Bachelors degree and 8 years of Manufacturing and Operations experience OR Associates degree and 10 years of Manufacturing and Operations experience OR High school diploma/GED and 12 years of Manufacturing and Operations experience OR Basic Qualifications: Doctorate degree and 2 years of Manufacturing and Operations experience OR Masters degree and 6 years of Manufacturing and Operations experience OR Bachelors degree and 8 years of Manufacturing and Operations experience OR Associates degree and 10 years of Manufacturing and Operations experience OR High school diploma/GED and 12 years of Manufacturing and Operations experience OR Basic Qualifications: Doctorate degree and 2 years of Manufacturing and Operations experience OR Masters degree and 6 years of Manufacturing and Operations experience OR Bachelors degree and 8 years of Manufacturing and Operations experience OR Associates degree and 10 years of Manufacturing and Operations experience OR High school diploma/GED and 12 years of Manufacturing and Operations experience OR Basic Qualifications: Doctorate degree and 2 years of Manufacturing and Operations experience OR Masters degree and 6 years of Manufacturing and Operations experience OR Bachelors degree and 8 years of Manufacturing and Operations experience OR Associates degree and 10 years of Manufacturing and Operations experience OR High school diploma/GED and 12 years of Manufacturing and Operations experience OR Basic Qualifications: Doctorate degree and 2 years of Manufacturing and Operations experience OR Masters degree and 6 years of Manufacturing and Operations experience OR Bachelors degree and 8 years of Manufacturing and Operations experience OR Associates degree and 10 years of Manufacturing and Operations experience OR High school diploma/GED and 12 years of Manufacturing and Operations experience OR Basic Qualifications: Doctorate degree and 2 years of Manufacturing and Operations experience OR Masters degree and 6 years of Manufacturing and Operations experience OR Bachelors degree and 8 years of Manufacturing and Operations experience OR Associates degree and 10 years of Manufacturing and Operations experience OR High school diploma/GED and 12 years of Manufacturing and Operations experience OR Basic Qualifications: Doctorate degree and 2 years of Manufacturing and Operations experience OR Masters degree and 6 years of Manufacturing and Operations experience OR Bachelors degree and 8 years of Manufacturing and Operations experience OR Associates degree and 10 years of Manufacturing and Operations experience OR High school diploma/GED and 12 years of Manufacturing and Operations experience OR Basic Qualifications: Doctorate degree and 2 years of Manufacturing and Operations experience OR Masters degree and 6 years of Manufacturing and Operations experience OR Bachelors degree and 8 years of Manufacturing and Operations experience OR Associates degree and 10 years of Manufacturing and Operations experience OR High school diploma/GED and 12 years of Manufacturing and Operations experience OR Basic Qualifications: Doctorate degree and 2 years of Manufacturing and Operations experience OR Masters degree and 6 years of Manufacturing and Operations experience OR Bachelors degree and 8 years of Manufacturing and Operations experience OR Associates degree and 10 years of Manufacturing and Operations experience OR High school diploma/GED and 12 years of Manufacturing and Operations experience OR Basic Qualifications: Doctorate degree and 2 years of Manufacturing and Operations experience OR Masters degree and 6 years of Manufacturing and Operations experience OR Bachelors degree and 8 years of Manufacturing and Operations experience OR Associates degree and 10 years of Manufacturing and Operations experience OR High school diploma/GED and 12 years of Manufacturing and Operations experience OR Basic Qualifications: Doctorate degree and 2 years of Manufacturing and Operations experience OR Masters degree and 6 years of Manufacturing and Operations experience OR Bachelors degree and 8 years of Manufacturing and Operations experience OR Associates degree and 10 years of Manufacturing and Operations experience OR High school diploma/GED and 12 years of Manufacturing and Operations experience OR Basic Qualifications: Doctorate degree and 2 years of Manufacturing and Operations experience OR Masters degree and 6 years of Manufacturing and Operations experience OR Bachelors degree and 8 years of Manufacturing and Operations experience OR Associates degree and 10 years of Manufacturing and Operations experience OR High school diploma/GED and 12 years of Manufacturing and Operations experience OR Basic Qualifications: Doctorate degree and 2 years of Manufacturing and Operations experience OR Masters degree and 6 years of Manufacturing and Operations experience OR Bachelors degree and 8 years of Manufacturing and Operations experience OR Associates degree and 10 years of Manufacturing and Operations experience OR High school diploma/GED and 12 years of Manufacturing and Operations experience OR Basic Qualifications: Doctorate degree and 2 years of Manufacturing and Operations experience OR Masters degree and 6 years of Manufacturing and Operations experience OR Bachelors degree and 8 years of Manufacturing and Operations experience OR Associates degree and 10 years of Manufacturing and Operations experience OR High school diploma/GED and 12 years of Manufacturing and Operations experience OR Basic Qualifications: Doctorate degree and 2 years of Manufacturing and Operations experience OR Masters degree and 6 years of Manufacturing and Operations experience OR Bachelors degree and 8 years of Manufacturing and Operations experience OR Associates degree and 10 years of Manufacturing and Operations experience OR High school diploma/GED and 12 years of Manufacturing and Operations experience OR Basic Qualifications: Doctorate degree and 2 years of Manufacturing and Operations experience OR Masters degree and 6 years of Manufacturing and Operations experience OR Bachelors degree and 8 years of Manufacturing and Operations experience OR Associates degree and 10 years of Manufacturing and Operations experience OR High school diploma/GED and 12 years of Manufacturing and Operations experience OR Basic Qualifications: Doctorate degree and 2 years of Manufacturing and Operations experience OR Masters degree and 6 years of Manufacturing and Operations experience OR Bachelors degree and 8 years of Manufacturing and Operations experience OR Associates degree and