Senior Manager, Cost Accounting

Inventory and Cost Accounting

Own end-to-end inventory and cost accounting processes, including accurate month-end and quarter-end close, reconciliations, variance analysis, and reporting.

Own COGS analytics and reporting, including development and maintenance of margin and variance analyses to support business decision-making.

Oversee standard costing processes, including cost updates, revaluations, impact analysis, and investigation of significant variances.

Analyze material, labor, external, and overhead costs to identify root causes and drive cross-functional, sustainable improvements.

Define and report key cost and operational metrics, ensuring costing methodologies comply with GAAP and internal policies.

Inventory Management, Controls & Compliance

Oversee cycle count programs and the year-end wall-to-wall physical inventory, ensuring compliance with SOX, GAAP, and company policies.

Ensure inventory variances are timely investigated, reviewed, and properly recorded with appropriate audit documentation.

Partner with Operations, Supply Chain, Quality, and R&D to ensure accurate inventory existence, valuation, and completeness.

Serve as a primary contact for internal and external auditors; support inventory-related walkthroughs, testing, and remediation.

Design, document, and maintain effective SOX controls related to inventory and cost accounting, driving continuous improvement in control effectiveness.

Systems, Process Improvement & Leadership

Support the design and implementation of automated COGS reporting, partnering with IT and Data teams to improve accuracy, timeliness, scalability, and reduce manual effort.

Drive ERP and system enhancements and process improvements to strengthen data accuracy, automation, and internal controls.

Lead, mentor, and develop the cost accounting team; set clear expectations, provide coaching, and support professional growth.

Skills and Requirements

• 8+ years of progressive experience supporting in-house manufacturing, preferably in a Lab Service Operations environment.
• Bachelor's degree in accounting, finance or related field; CPA or MBA a plus.
• Highly proficient in Microsoft Office, specifically Excel.
• Integrated MRP systems knowledge preferred.
• Extensive ERP experience, Oracle Fusion inventory and materials movement experience strongly preferred.
• A solutions-oriented team player who enjoys a dynamic work environment.
• Ability to communicate complex information in a clear and concise manner.
• Ability to effectively work with all levels and cross-functionally within the company including Senior Management.
• Strong analytical skills, with a sharp focus on details.
• AI & Digital Fluency: Demonstrate curiosity, sound judgment, and the ability to critically evaluate and responsibly leverage AI-enabled tools in accordance with company policies, ethical standards, and regulatory requirements to improve the efficiency, effectiveness, and quality of work.

Hybrid Work Model

This section is applicable to onsite employees who are eligible for hybrid work location as specified by management and related policies. Guardant has defined days for in-person/onsite collaboration and work-from-home days for individual-focused time. All U.S. employees who live within 50 miles of a Guardant facility will be required to be onsite on Mondays, Tuesdays, and Thursdays. We have found aligning our scheduled in-office days allows our teams to do the best work and creates the focused thinking time our innovative work requires. At Guardant, our work model has created flexibility for better work-life balance while keeping teams connected to advance our science for our patients.

Pay and Benefits

• The annualized base salary ranges for the primary location and any additional locations are listed below.
• This range does not include benefits or, if applicable, bonus, commission, or equity.
• Each candidate’s compensation offer will be based on multiple factors including, but not limited to, geography, experience, education, job-related skills, job duties, and business need.
• Primary Location: Palo Alto, CA Base Pay Range: $163,800 - $225,250
• Other US Location(s): Base Pay Range: $139,230 - $191,463
• If the role is performed in Colorado, the pay range for this job is: $147,420 - $202,725

Physical Demands and Work Environment

• Employee may be required to lift routine office supplies and use office equipment.
• Majority of the work is performed in a desk/office environment; however, there may be exposure to high noise levels, fumes, and biohazard material in the laboratory environment.

Equal Opportunity Employer

Guardant Health is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.