Senior Laboratory Coordinator - Cancer Center (Bioanalytical Lab)

Job Responsibilities

• Develop, validate, and apply UHPLC-MS/MS-based assays for quantitation of drugs, drug metabolites, and other small molecules in research samples collected from patients in clinical trials.
• Maintain records for sample tracking in the lab and perform calibrations and minor maintenance on instruments and equipment.
• Utilize proven proficiency in basic laboratory skills — calibration and use of balances, pipettors, centrifuges, sample evaporators.
• Perform, interpret, and report results from quantitative analytical methods.
• Collaborate with Cancer Center laboratory and clinical research staff to ensure transfer and processing of samples and communication of results in a timely manner.
• Ensure all requirements for sample integrity have been met (positive identification of patient, visit, and time; traceable records from sample transfer through final data delivery, etc.).
• Recognize sources of error in sample identification, processing, or analysis and initiate corrective action when indicated.
• Affirm that the appropriate personnel have been contacted and the incident documented according to SOP’s.
• Maintain records for sample tracking in the lab and performs calibrations and minor maintenance on instruments and equipment.
• Participate in quality assurance/quality improvement activities related to sample transfer and storage, sample processing, sample analysis, and data integrity and reporting.

Qualifications

• Four (4) years of relevant work experience.
• Experience with basic laboratory skills - calibration and use of balances, pipettors, centrifuges, sample evaporators.
• Experience performing, interpreting, and reporting results from quantitative analytical methods.
• Experience with mass spectrometry.
• Experience with sample preparation techniques (protein precipitation, solid phase extraction, liquid-liquid extraction).
• Experience with quantitative UHPLC-MS/MS procedures.
• Experience in a regulated laboratory (GLP or equivalent).
• Laboratory experience supporting clinical trials.