Senior Lab Researcher - Seibold Lab

About the role

The Seibold Laboratory is seeking a passionate and highly motivated Senior Lab Researcher to join our cutting-edge, NIH-funded research team. Our group is an interdisciplinary laboratory that brings together diverse molecular and cellular skill sets to advance human translation disease research in asthma and allergic diseases. We integrate robotic, high-throughput processing of biospecimens from large human cohorts with scalable primary airway and immune cell/tissue culture models for mechanistic studies, alongside multi-omic molecular/genetic profiling to define complex disease pathobiology.

Lab Platforms and Capabilities

• Robotic and automated sample processing to support high-throughput human cohort studies.
• Primary airway epithelial and immune cell culture models for mechanistic experiments.
• Advanced molecular and genetic techniques, including RNA-seq library construction, single-cell RNA-seq, and spatial transcriptomics.
• Rigorous data capture, quality control, and compliant laboratory practices to support translational research.

Essential Duties

• Plans, develops, operates, records, collaborates and reports on research projects.
• Performs as the technical advisor on techniques involving complex analyses utilizing highly sophisticated techniques.
• Provides guidance to laboratory staff, including technicians, support and auxiliary staff.
• Plans, organizes and leads the work of Lab Researchers and Lab Technicians.
• Serves as the primary contact with the research staff for technical services on major techniques, recording devices and statistical procedures relative to the specifically assigned field.
• Reviews quality control of new or modified laboratory techniques which may affect any part of major projects.
• Prepares statistical tabulations, using a calculator or computer.
• Demonstrates enhanced proficiency in data analysis, preparation of glassware, extraction and plating procedures, programming and mathematical ordering systems.
• Oversees supply functions, inventory control, equipment use and maintenance, and animal care and ordering, as needed.
• Maintains compliance with all institutional / safety training requirements.
• Maintains laboratory records, supplies, samples in an organized manner (such as a laboratory notebook and sample storage record).

Qualifications

• Education: Bachelor's Degree required.
• Work Experience: 5 years of Laboratory Experience required. A Master’s Degree and 3 years of laboratory experience may be substituted for the required 5 years of work experience.

Skills

• Experience with high-throughput workflows and/or laboratory automation (robotics).
• Experience with primary airway epithelial culture and/or immune cell culture systems.
• Hands-on experience with RNA-seq library preparation, single-cell RNA-seq, and/or spatial transcriptomics.
• Demonstrated ability to mentor staff and coordinate multi-project laboratory operations.

Benefits

Comprehensive Medical Coverage: Multiple Cigna health plans for Colorado, regional office and remote employees. Health Savings Accounts (HSA) and Flexible Spending Accounts (FSA) available to pair with some plans.
Paid Time Off: Generous PTO accruals to use for vacation and sick days, and six paid holidays, all compliant with Colorado state sick leave regulations.
Dental & Vision Plans: Coverage effective the first of the month after hire.
Retirement Savings: 403(b) plan with employer contributions after two years.
Wellness Incentives: Earn up to $200 annually for preventive health activities.
Tuition Reimbursement: Up to $5,250 annually for full-time and part-time employees.
Child Care Assistance: Childcare Flex Spending Account (FSA) with annual employer contribution.
Loan Forgiveness: Public Service Loan Forgiveness (PSLF) eligible employer.
Disability & Life Insurance: Employer-paid plans and optional buy-up choices.
Voluntary Benefits: Full suite of coverage options such as Accident, Hospital Indemnity and Legal Plan.
Exclusive Discounts: Savings on local services, insurance, and RTD bus passes.