Senior Infrastructure Engineer

Position Summary

The Senior Infrastructure Engineer is responsible for the administration, maintenance, security, and continuous improvement of Cabaletta Bio’s infrastructure and cloud platforms. This role provides hands-on technical support for AWS, Windows and Linux server environments, networking, firewalls, cybersecurity controls, backup and disaster recovery capabilities, and emerging platform technologies.

Essential Duties and Responsibilities

• Infrastructure Administration
• Administer and support AWS cloud infrastructure, including EC2, VPCs, security groups, storage services, monitoring, and related cloud resources.
• Administer, maintain, and troubleshoot Windows Server and Linux server environments.
• Maintain infrastructure documentation, architecture diagrams, technical standards, and operating procedures, and assist with development and implementation of operational processes and technical best practices.
• Network and Connectivity
• Support, maintain, and troubleshoot network infrastructure, including firewalls, VPN connectivity, routing, DNS, DHCP, and wireless networking services, across cloud, server, and application environments.
• Aid in network design reviews and infrastructure improvements, and collaborate with managed service providers and infrastructure vendors to resolve complex technical issues.
• Cloud and Platform Services
• Design and support cloud-native and containerized workloads utilizing technologies such as Docker, ECS, EKS, and related platforms.
• Assist with application hosting, platform administration, and infrastructure services supporting internal business systems and scientific computing workloads, and participate in cloud modernization, infrastructure automation, and platform engineering initiatives.
• Support infrastructure requirements for data platforms, internal applications, and future AI-enabled solutions.
• Cybersecurity and Risk Management
• Implement and maintain infrastructure security controls and cybersecurity best practices.
• Support vulnerability remediation, system hardening, patch management, access controls, and security monitoring activities.
• Review infrastructure security recommendations and assist with implementation of corrective actions, collaborating with internal and external security resources to address identified risks.
• Support security audits, assessments, and compliance initiatives as required.
• Business Continuity and Disaster Recovery
• Support backup administration, recovery procedures, disaster recovery planning, and infrastructure resilience initiatives, including participation in DR exercises, testing activities, and business continuity planning.
• Maintain documentation supporting recovery procedures and infrastructure continuity requirements.
• Vendor and Service Coordination
• Serve as a technical point of contact for managed service providers, cloud partners, and infrastructure vendors.
• Coordinate technical activities, projects, escalations, and support requests across external partners, reviewing vendor and partner recommendations to provide technical input and implementation support.
• Customer Service and Collaboration
• Communicate effectively with business users, scientific teams, and technology partners, providing technical guidance and support during infrastructure-related incidents, projects, and technology initiatives.
• Partner closely with the Senior IT Systems Administrator and broader IT team to support enterprise technology services.

Qualifications

• Required Qualifications:
• Bachelor’s degree in Information Technology, Computer Science, Engineering, or a related field, or equivalent experience.
• 5+ years of progressive infrastructure administration experience.
• Experience supporting biotechnology, pharmaceutical, or life sciences organizations, including work within GxP-regulated environments and experience with computer system validation (CSV), change control processes, and compliance-driven operations.
• Experience administering AWS cloud environments.
• Strong experience administering Linux and Windows Server environments.
• Experience supporting network infrastructure, firewalls, VPNs, DNS, and related technologies.
• Foundational cybersecurity experience, including vulnerability remediation, system hardening, access management, and security best practices.
• Experience supporting backup, recovery, and disaster recovery processes.
• Strong troubleshooting, root cause analysis, and problem-solving skills.
• Strong written and verbal communication skills with the ability to work effectively with both technical and non-technical stakeholders.
• Ability to work independently while collaborating effectively with internal teams, vendors, and external partners.
• Preferred Qualifications:
• Experience supporting scientific, laboratory, clinical, manufacturing, quality, or regulatory business functions, including validated applications and infrastructure platforms.
• Experience with Docker, containerized workloads, ECS, EKS, or Kubernetes.
• Experience with infrastructure automation and scripting using PowerShell, Bash, Python, or similar technologies.
• Experience supporting hybrid cloud environments.
• AWS, Microsoft, Linux, networking, or security certifications.

Physical Requirements

• Ability to sit and work at a computer for extended periods of time.
• Ability to occasionally lift and move technology equipment weighing up to 25 pounds.
• Ability to travel occasionally between company locations, data centers, or vendor sites as needed.

Reporting Structure

Reports to the Director, Information Technology and Data Sciences.