Senior Director, US Rare Disease Value and Access

Main responsibilities

• Partner with GM and senior leadership to set direction for pricing, contracting, GTN, and reimbursement across rare disease portfolio
• Create evidence-based market access strategies that maximize formulary adoption and patient access
• Create compelling value propositions for payers, providers, and key stakeholders
• Oversee and optimize GTN across the therapeutic area (pricing, rebates, and discounts by channel)
• Monitor GTN performance and deliver recommendations to senior leadership to protect profitability
• Collaborate with Finance, Forecasting, Trade, Legal, and Patient Support Services to improve net sales
• Lead GTN pull-through across all channels and geographies based on formulary position
• Anticipate changes in regulatory and reimbursement landscape; ensure sustained compliance and access
• Develop primary payer research and advisory board programs to close market access knowledge gaps
• Champion launch readiness for landmark AATD therapy (1H 2027) across payer, access, and reimbursement dimensions
• Monitor competitive landscape and payer behavior in partnership with Business Insights & Solutions
• Define KPIs and track progress against access and financial targets
• Balance brand objectives and patient access priorities when they are in conflict
• Build, develop, and lead a high-performing team of 2 direct reports

About you

• Role Overview: The Senior Director, US Rare Disease Value and Access owns the value, evidence, pricing, and reimbursement strategy that turns an approved rare disease therapy into a covered, affordable, accessible one. The role spans HEOR and evidence generation, pricing and contracting, payer engagement, and policy working backwards from what payers need to be convinced of value, often with limited trial data. In rare disease, access is not a downstream function: it is a strategic driver that shapes the commercial case from before launch.
• Qualifications: Bachelor's degree required; advanced degree (MBA, PharmD, MPH, MS, PhD) strongly preferred; 10+ years of market access and payer experience, gained within the pharmaceutical/biotech industry or from external environments such as payer organizations, managed care, consulting, or health economics firms; 7+ years of leadership experience managing teams and cross-functional initiatives; Demonstrated expertise in payer access strategy: pricing, contracting, reimbursement, formulary management; Proven track record in GTN management and financial modeling; Strong financial acumen including P&L impact and pricing strategy; Experience with value proposition development and payer evidence generation; Experience in rare disease or specialty therapeutics preferred; Excellent communication, negotiation, and executive influence skills; Ability to navigate complex, highly regulated environments while managing multiple priorities