(Senior) Director, Translational Medicine and Diagnostics

Responsibilities

• Build the Function: Build and lead insitro's translational medicine function, from IND/CTA through clinical proof-of-concept, across biologics, oligonucleotides, and small molecules
• Lead Key Assets: Serve as translational lead for advanced pre-clinical and initial clinical-stage assets
• Own End-to-End Strategy: Be accountable for translational medicine strategy, GCP adherence, and regulatory-authority interactions, including biospecimen CRO selection and oversight
• Biomarker Science & Patient Stratification: Design Stratification Strategies and Generate Proof-of-Mechanism Evidence
• Regulatory Strategy, Partnership & Influence: Interpret Regulatory Requirements, Partner Across Functions, and Shape the Field

About You

• Experience & Qualifications: Advanced Degree in life sciences, technology, chemistry, or a related discipline, or equivalent practical experience; 10+ years of experience in translational science in biotech and/or pharma, including direct experience as a translational lead delivering therapeutics and diagnostic biomarkers from FIH through proof-of-concept to NDA/BLA submission; Experience applying AI/ML approaches to drug discovery and development; Deep understanding of diagnostic and device regulations, good clinical practice, clinical trial design and execution, clinical pharmacology, biostatistics, and the application of computation to drug development

Core Competencies

• Cross-Functional Collaborator: Track record of communicating and collaborating effectively with diverse stakeholders across clinical, translational, computational, and life sciences functions
• Motivating Leader: Strong interpersonal skills that inspire others to do their best work
• Patient-Driven: Genuine passion for bringing better medicines to patients in need

Compensation & Benefits

At Insitro, our target starting salary for successful US-based applicants for this role is $224,000 - $299,000. To determine starting pay, we consider multiple job-related factors including a candidate's skills, education and experience, market demand, business needs, and internal parity. We may also adjust this range in the future based on market data.

This role is eligible for participation in our Annual Performance Bonus Plan (based on company targets by role level and annual company performance) and our Equity Incentive Plan, subject to the terms of those plans and associated policies.

In addition, Insitro also provides our employees with a 401(k) plan with employer matching for contributions, excellent medical, dental, and vision coverage as well as mental health and well-being support, an open, flexible vacation policy, paid parental leave of at least 16 weeks to support parents who give birth, and 10 weeks for a new parent (inclusive of birth, adoption, fostering, etc), quarterly budget for books and online courses for self-development, a new hire stipend for home office setup, monthly cell phone & internet stipend, access to free onsite baristas and daily lunch for employees who are either onsite or hybrid, and access to a free commuter bus network that provides transport to and from our South San Francisco HQ from locations all around the Bay Area.

insitro is an equal opportunity employer. All applicants will be considered for employment without attention to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status. We believe diversity, equity, and inclusion need to be at the foundation of our culture. We work hard to bring together diverse teams–grounded in a wide range of expertise and life experiences–and work even harder to ensure those teams thrive in inclusive, growth-oriented environments supported by equitable company and team practices.