Senior Director, Program Team Lead

About the Company

At Editas Medicine, our mission and commitment is to harness the power and potential of CRISPR gene editing to develop a robust pipeline of medicines for people living with serious diseases around the world. Our goal is to discover, develop, manufacture, and commercialize transformative, durable genomic medicines for many diseases.

We're a team of passionate problem solvers, driven by a shared purpose to serve people living with serious diseases. We succeed together through collaboration, mutual respect, and innovation. If you want to be part of a team where your voice is heard and respected, and where you can operate at the forefront of gene editing, join us.

About the Role

The primary focus of this role in the next 12 months is to advance our lead in vivo development candidate, EDIT-401, by leading program strategy and driving disciplined, cross-functional execution. EDIT-401 is a potential best-in-class, one-time therapy designed to significantly reduce LDL cholesterol levels. This is a critical and highly visible role with the opportunity to expand as pipeline therapies advance in development.

Responsibilities

• Lead the Program Team, responsible for creating and developing the program strategy, goals, milestones, and operational plan including realistic timelines, budget and resource planning, risk assessment and mitigation planning in collaboration with functional heads.
• Enable high-quality, on-time governance decisions and drive decision-making and issue resolution within the team, pulling on applicable subject matter expertise as needed.
• Ensure cross-functional alignment and accountability for execution of the operational plan with a focus on high-impact activities, establishing clear owners, dependencies, and timelines across Nonclinical, CMC, Quality, Regulatory, and Development.
• Responsible for dissemination of comprehensive, timely, and high-quality program information to Senior Management, including appropriate escalation of issues as may be required.
• Continuously pressure-test timelines and critical paths, proactively identifying opportunities to streamline execution without compromising quality or budget.
• Establish proactive risk identification and mitigation frameworks, surface issues, and drive for their resolution.
• Leads ad-hoc cross-functional task forces, as needed, aiming at issue resolution or organizational efficiency.
• Challenge assumptions, timelines, and expenses at program level, pressure test plans, and create alternative scenarios to enable strategic and operational agility.
• Demonstrate ability to operate in the presence of ambiguity, make timely decisions, and adapt based on emerging data.
• Own the program-level budget, resource planning, and scenario assessments (evaluating cost, risk, and timelines) in collaboration with functional management.
• Build credibility and trust through recognition by functional leaders as a value-adding, enterprise-minded, decision-enabling partner.

Requirements

• A minimum of a bachelor's degree in life sciences or related subjects; advanced degrees (Ph.D or MBA) are desirable.
• 10+ years of experience in biotech/pharma, with 8+ years in program management supporting early-stage clinical development. Experience managing multiple programs at the same time is desirable.
• Solid understanding of science and experience with gene therapy programs is highly desirable.
• Proven track record of leading cross-functional teams in a matrixed environment.
• Excellent relationship-building skills and ability to earn trust and align diverse perspectives towards a shared goal.
• Strong understanding of preclinical development, IND-enabling studies, and early clinical trial operations. Experience across functional roles is desirable.
• Expert planning and tracking skills with mastery of project management tools and methodologies (e.g., Smartsheet, Microsoft Project, Office Timeline).
• Desirable leadership attributes include holding teams accountable with clarity and respect, and demonstrating impact with a focus on delivering outcomes. Comfort operating with urgency, limited infrastructure, and ambitious priorities.

Benefits

• Blue Cross Blue Shield PPO Medical Plan
• Company-funded Health Savings Account
• Dental and Vision Insurance
• Life and Disability Insurance
• Dependent Care Account
• Tuition Reimbursement
• 401(k) plan with company match
• Employee Assistance Plan
• Wellness Programs
• Flexible Paid Time Off policy

Pay

Salary Range: $265,000 - $290,000. The final salary offer will be determined based on a comprehensive assessment of the candidate's qualifications, including education, training, and relevant experience. Additional factors such as external market conditions, the role's criticality, and internal equity will also be considered.