Jobs · Healthcare · Massachusetts

Senior Director, Immunology

Vertex Pharmaceuticals · Boston, MA · 2 days ago
On-siteHealthcare$238k–$357k/yrFull-time

Responsibilities

  • Serve as Research Program Team Lead for 2+ programs driving cross-functional collaboration and alignment to achieve program goals
  • Develop strategy and build capabilities to advance novel, next gen drug discovery in T1D
  • Provide scientific, strategic, and organizational leadership for immunology research and drug discovery programs supporting the cell and genetic therapy portfolio.
  • Develop and execute innovative immunomodulatory and translational immunology strategies to advance allogeneic transplantation and other immune-mediated therapeutic opportunities.
  • Lead cross-functional teams to identify, validate, and advance novel therapeutic targets and candidates from discovery through development while ensuring timely, high-quality execution and communication of research results.
  • Shape research and portfolio strategy through deep immunology expertise, data-driven conclusions, emerging scientific advances, and balanced pursuit of innovation against defined project objectives.
  • Build and maintain productive collaborations across internal functions and with external academic, clinical, industry, and pharma partners.
  • Manage group resources, budgets, hiring, staff activities, and goal setting to align scientific capabilities and personnel priorities with department and corporate objectives.
  • Mentor and develop high-performing scientists while fostering scientific rigor, technical excellence, ethical publication and patenting practices, and clear communication across the organization.

Requirements

  • PhD/MD (or equivalent degrees) in immunology, molecular biology, cell biology, molecular pathology, or related disciplines
  • 12+ years of industry or equivalent experience in Immunology
  • Experience in supervising others work, leadership of cross functional teams and contributing to discovery and development programs to IND, FIM and PoC.

Knowledge & Skills

  • Deep scientific expertise in immunology, immunology-driven drug discovery, and translational science, including biomarker development and clinical application of preclinical findings.
  • Proven ability to advance therapeutic programs from target discovery through candidate selection across modalities, including cell and genetic therapies, biologics, small molecules, and nucleic acid-based medicines.
  • Strong scientific judgment and strategic thinking to shape portfolio strategy, guide investment decisions, and identify productive in vivo, ex vivo, and translational approaches.
  • Expertise in pharmacological and immunological models of autoimmunity, allo-transplantation, type 1 diabetes, allo-islet transplantation, and immune response analysis in murine, non-human primate, and human systems.
  • Advanced technical expertise in cellular and molecular immunology methods, such as multicolor flow cytometry, ex vivo immune cell culture and functional assays, immunohistochemistry, immunophenotyping, ELISA, cell sorting, RNA-seq, epigenetics, and complex dataset analysis.
  • Exceptional communication, presentation, and leadership skills, with demonstrated ability to mentor talent, develop teams, and represent high standards of scientific integrity and organizational practice.

Similar jobs