Senior Director, Head of Clinical Pharmacology

For our client, we are seeking a Senior Director, Head of Clinical Pharmacology to join the team of a leader in the Pharmaceuticals & Biotech space. This leader will oversee clinical pharmacology and translational PK/PD strategy across the full development lifecycle, from early candidate selection through regulatory submission and market authorization. The role will serve as a key scientific partner to cross-functional teams, helping shape dose selection, exposure-response strategy, and program advancement. This person will also lead a team, manage external collaborations, and contribute to resource planning and budget oversight in support of the broader pipeline. Location: Remote - US based candidates only, no visa sponsorship available Compensation: $235,500 – $329,500 annually Responsibilities Oversee clinical pharmacology and translational PK/PD operations across all development stages Act as a technical expert on cross-functional project teams, providing strategic input Develop clinical pharmacology strategies for regulatory decisions from pre-IND to market authorization Select and execute modeling approaches to inform dose selection and optimization Author and provide input for regulatory documents and submissions Collaborate with cross-functional teams to support program advancement Manage collaborations with external vendors and partners Generate and manage departmental budgets and optimize resource allocation Lead and develop the Clinical Pharmacology and Translational PK/PD team Qualifications PhD, PharmD, or MD with 13+ years in Clinical Pharmacology or related fields Mastery of pharmacokinetic concepts and methodologies Expertise in PK/PD, PopPK, and exposure-response modeling Extensive experience in translational and clinical pharmacology from candidate selection to market authorization Strong understanding of regulatory requirements and experience with submissions Experience with biologics, especially monoclonal antibodies and bispecifics; oncology experience preferred Proficiency in standard PK analysis and graphing programs Benefits Health and welfare benefit plans Non-accrual paid time off Company shutdown for holidays Commuter benefits 401K match Daily lunch provided in the office Our client is an equal opportunity employer. We encourage you to apply even if you don’t meet every qualification—your background could be exactly what this team needs.