Senior Director, Global Medical Affairs - Nephrology

About the Role

The Medical Affairs Senior Director provides medical and scientific leadership in the assigned Therapeutic Area(s) (TA). This role will work closely with a cross-functional group to ensure that scientific and medical strategies are aligned with broader corporate and key stakeholder needs and will ensure the flawless execution of Nephrology medical plans, with a main focus on Kidney programs.

Responsibilities

• Support medical affairs activities for kidney indications (e.g., IgAN, AMKD, and future indications).
• Critically interpret scientific data and determine its potential impact on the scientific and medical understanding of assigned products.
• Develop medical affairs plans, including Launch and Life Cycle Management plans.
• Share country/regional insights with global teams to align global medical strategies with local needs.
• Provide fair and balanced medical information and education to healthcare professionals and payers to support the safe and effective use of Vertex drugs.
• Foster patient access to Vertex drugs by supporting the commercial organization in preparing/reviewing reimbursement dossiers and presenting scientific data to key stakeholders.
• Perform or oversee medical/scientific training for field medical teams, commercial, and other internal stakeholders.
• Contribute to the local Brand Team, representing the TA with scientific and medical expertise while ensuring activities address patient well-being and data integrity.
• Ensure compliance at the country level with company policies, medical affairs SOPs, GCP, and ICH.
• Assess local promotional materials to ensure all claims are fully supported by scientific data and presented accurately, fairly, and balanced.

Requirements

• Deep understanding of global medical, regulatory, and commercial (including payer) environments.
• Excellent understanding of government and industry guidelines, regulations, and laws for appropriate scientific/medical exchange and communication with external stakeholders (e.g., healthcare providers, payers, advocacy bodies).
• Experience in market access in key countries.
• Experience in writing or reviewing scientific communications.
• Excellent written and oral communication skills to influence others internally and externally.
• Ability to develop relationships in a highly matrixed environment, as well as external relationships with leaders and industry experts.
• Proven ability to plan, initiate, and complete projects within allotted time frames while delivering high-quality results.
• Ability to engage in positive dialogue and resolve conflicts constructively.
• Ability to work within a multi-disciplinary and multi-cultural team on common projects and goals at national and regional levels.

Qualifications

• M.D. degree or equivalent, PhD, or PharmD.
• Typically requires 11 years of experience or an equivalent combination of education and experience.

Pay

The pay range for this role is $252,000 - $378,000. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary will be based on skills, competencies, experience, and other job-related factors permitted by law.

Benefits

• Inclusive market-leading medical, dental, and vision benefits.
• Generous paid time off, including a week-long company shutdown in the Summer and Winter.
• Educational assistance programs, including student loan repayment.
• Generous commuting subsidy.
• Matching charitable donations.
• 401(k) retirement plan and additional financial benefits.

Schedule

This is a Hybrid-Eligible role, allowing you to choose between:

• Hybrid: Work remotely up to two days per week.
• On-Site: Work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.