Senior Clinical Research Associate - Oncology - 174241

About the role

Piper Companies is seeking an experienced Senior Clinical Research Associate (CRA) to support Phase II–III Oncology clinical studies in a dynamic, sponsor-facing environment. This role will be responsible for overseeing site performance, ensuring regulatory compliance, and driving successful trial execution through strong site relationships and hands-on monitoring activities. This is a full time opportunity that requires regional travel and is primarily in the West, Mountain, and Central times. Must be located within reasonable distance of a major airport and willing to travel regionally as required.

Responsibilities

• Independently monitoring Phase II–III Oncology clinical trials to ensure compliance with study protocols, ICH-GCP guidelines, and regulatory requirements.
• Conducting site initiation, routine monitoring, and closeout visits while maintaining high-quality oversight of investigative sites.
• Performing source data review (SDR), source data verification (SDV), and case report form (CRF) review to ensure accurate and inspection-ready study data.
• Building strong partnerships with investigative sites to support enrollment goals, protocol adherence, and overall study success.
• Collaborating directly with sponsors, study teams, and site personnel while providing regular updates on site performance and trial progress.

Qualifications

• 4+ years of Clinical Research Associate experience, including significant experience independently monitoring Oncology clinical trials.
• Strong knowledge of ICH-GCP guidelines, FDA regulations, clinical trial operations, and site management best practices.
• Experience supporting Phase II and Phase III studies with responsibility for site oversight, monitoring, and issue resolution.
• Proven ability to conduct site initiation, interim monitoring, and closeout visits independently.
• Strong sponsor-facing communication skills and experience working directly with biotechnology or pharmaceutical clients.
• Ability to manage multiple investigative sites, prioritize competing demands, and work effectively with minimal supervision.

Pay

Salary range: $120,000 - $145,000

Benefits

• Medical
• Dental
• Vision
• 401k
• PTO
• Holidays
• Sick leave as required by law