Senior Clinical Research Associate - CNS/Cardiovascular - 174240

About the role

Piper Companies is seeking an experienced Senior Clinical Research Associate (CRA) to support CNS and Cardiovascular clinical studies in a dynamic, sponsor-facing environment. This role will be responsible for overseeing site performance, ensuring regulatory compliance, and driving successful trial execution through strong site relationships and hands-on monitoring activities. This is a full‑time opportunity that requires regional travel and can be located anywhere in the United States.

Responsibilities

• Independently monitor Phase II–III CNS and Cardiovascular clinical trials to ensure compliance with study protocols, ICH‑GCP guidelines, and regulatory requirements.
• Conduct site initiation, routine monitoring, and closeout visits while maintaining high‑quality oversight of investigative sites.
• Perform source data review (SDR), source data verification (SDV), and case report form (CRF) review to ensure accurate and inspection‑ready study data.
• Build strong partnerships with investigative sites to support enrollment goals, protocol adherence, and overall study success.
• Collaborate directly with sponsors, study teams, and site personnel while providing regular updates on site performance and trial progress.

Qualifications

• 1+ years of Clinical Research Associate experience, including significant experience independently monitoring CNS and/or Cardiovascular clinical trials.
• Strong knowledge of ICH‑GCP guidelines, FDA regulations, clinical trial operations, and site management best practices.
• Experience supporting Phase II and Phase III studies with responsibility for site oversight, monitoring, and issue resolution.
• Proven ability to conduct site initiation, interim monitoring, and closeout visits independently.
• Strong sponsor‑facing communication skills and experience working directly with biotechnology or pharmaceutical clients.
• Ability to manage multiple investigative sites, prioritize competing demands, and work effectively with minimal supervision.
• Must be located within reasonable distance of a major airport and willing to travel regionally as required.

Pay

Salary range: $100,000 – $115,000.

• Medical
• Dental
• Vision
• 401(k)
• Paid time off (PTO)
• Holidays
• Sick leave as required by law