Senior Biological Data Scientist

About GondolaBio

GondolaBio is a clinical-stage biopharmaceutical company focused on developing breakthrough therapeutics for genetic diseases. Originally carved out in 2024 as an independent sister company to BridgeBio after securing $300M in private financing, GondolaBio leverages cutting-edge biological research to discover, create, test, and deliver transformative medicines to treat patients who suffer from genetic diseases.

About the Role

You will design and execute integrative computational analyses spanning multiomics datasets to accelerate therapeutic discovery in rare and genetically defined diseases. Working independently in a collaborative, data-driven environment, you will identify opportunities where diverse biological data can answer challenging scientific questions, generate therapeutic hypotheses, and advance biomarker discovery. This role involves leveraging AI-enabled computational approaches while applying sound scientific judgment throughout the research process.

Responsibilities

• Design, execute, and interpret integrative computational analyses spanning transcriptomic, proteomic, genetic, and other biological data modalities to support target identification, biomarker discovery, mechanism-of-action studies, and translational research.
• Integrate public and internal datasets to generate, prioritize, and refine therapeutic hypotheses across diverse disease programs.
• Collaborate closely with cross-functional scientists to translate computational analyses into actionable scientific insights.
• Communicate results clearly and effectively through presentations, written reports, and contributions to scientific publications and conferences.

Requirements

• PhD in Computational Biology, Bioinformatics, Genetics, or a related quantitative discipline with 5+ years of industry and/or postdoctoral experience applying computational methods to large-scale biological datasets.
• Demonstrated experience integrating transcriptomic, proteomic, genetic, and related biological datasets to answer complex scientific questions.
• Experience supporting biomarker discovery, translational research, or target identification in a biotechnology or pharmaceutical setting.
• Working proficiency in Python for scientific computing and data analysis.
• Comfortable tackling unfamiliar biological problems by rapidly learning new disease areas, identifying appropriate datasets, and integrating diverse evidence into actionable scientific insights.
• Excellent communication skills and the ability to thrive as an independent contributor in a collaborative, fast-moving research environment.

Preferred Qualifications

• Experience with transcriptomic approaches, particularly single-cell RNA sequencing.
• Experience with spatial transcriptomics or related cellular profiling technologies is strongly preferred.
• Experience using large language models and agentic AI workflows to accelerate computational biology research, with appropriate scientific validation of outputs.
• Deep expertise in at least one area of computational biology while contributing broadly across multiomics analyses.

Schedule

This is a U.S.-based remote role with periodic travel (quarterly or as needed) to GondolaBio's Palo Alto office or conference locations.

Benefits

• Patient Days, where employees hear directly from individuals living with the conditions the company seeks to impact.
• A culture inspired by values: put patients first, think independently, be radically transparent, every minute counts, and let the science speak.
• Decentralized model enabling program teams to focus on advancing science and helping patients, with decision-making power in the hands of those closest to the science.
• Ownership of your program vision and career path in a collaborative, fast-paced, data-driven environment.
• Access to learning and development resources to support professional growth.
• Robust and market-competitive compensation and benefits package, including base pay, performance bonus, equity, health, welfare, and retirement programs.
• Flexible PTO and rapid career advancement for strong performers.
• Potential to work on multiple GondolaBio programs across therapeutic areas over time.

Pay

The base pay range for this position is $155,000 to $205,000 per year. The actual compensation offered will be determined based on experience, skills, qualifications, and location. A bonus plan and equity will also be offered.