Senior Associate Scientist, High-throughput Molecular Biologist

About the role

The High-throughput Screening (HTS) team at Pfizer is seeking a molecular biology expert to support the development and evaluation of vaccine candidates. This role involves performing cell-based expression assays and automated screening workflows in a BSL-2 laboratory.

Responsibilities

• Perform RNA synthesis, characterization, and analytical assessments to support preclinical evaluation of vaccine candidates
• Design, execute, and troubleshoot cell-based assays to evaluate in vitro expression of vaccine candidates
• Collaborate with automation specialists to develop Hamilton STAR methods, translating manual workflows into automation-compatible, high-throughput screening methods
• Operate Hamilton STAR liquid handling platforms to execute automated workflows for efficient screening of vaccine candidates
• Collect, analyze, interpret, and summarize experimental data with a focus on accuracy, reproducibility, and scientific rigor
• Communicate experimental results and progress updates to team members and senior leadership in a clear and timely manner
• Maintain accurate and well-organized inventories of reagents and biological samples to support high-throughput operations
• Document and report findings in accordance with Standard Operating Procedures (SOPs) and Pfizer Laboratory Notebook Policy requirements

Qualifications

• Bachelor’s degree (BA/BS) in a relevant scientific discipline (e.g., Biology, Cell Biology, Molecular Biology) or Master’s degree with 0 to 3 years of experience
• Demonstrated proficiency in molecular biology techniques, including in vitro transcription, RNA analysis, and cell-based assays
• Hands-on experience working with mammalian cell culture systems and applying aseptic techniques in a laboratory setting
• Ability to independently design, execute, and analyze experiments, with confidence presenting and explaining data outcomes
• Strong attention to detail and commitment to data quality and documentation standards
• Proven ability to work collaboratively in a fast-paced, team-oriented environment
• Highly organized, detail-oriented, with strong written and verbal communication skills
• Proficiency in scientific computing and documentation tools, including Microsoft Excel, PowerPoint, SharePoint, and GraphPad Prism

Nice-to-Have

• Experience operating and/or supporting Hamilton STAR automation platforms, including method execution or development
• Experience operating or troubleshooting automation instruments such as KingFisher Apex
• Hands-on experience with molecular cloning and sequencing analysis
• Familiarity with LIMS, GeneData, or similar data management platforms

Physical/Mental Requirements

• Work primarily at the laboratory bench and at an office desk using a computer
• May involve lifting light loads, not more than 10 pounds
• Requires the ability to stand and reach inside the hardware environment of various laboratory robotic equipment

Pay

The annual base salary for this position ranges from $68,600.00 to $114,300.00. This position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 7.5% of the base salary.

Benefits

We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage.

Relocation Assistance

Relocation support may be available based on business needs and/or eligibility.

Equal Opportunity Employer

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA.