Senior AI Scientist, AI Products / Life Sciences

About the role

At Tempus, we are pursuing a mission to redefine precision medicine through data-driven insights. The AI Products group is a multidisciplinary group of AI scientists and engineers focused on developing AI-driven precision medicine and therapeutic solutions across the clinical and drug development lifecycle. As a Senior AI Scientist, you will operate at the intersection of machine learning and clinical science. You will research, design, and deploy cutting-edge multimodal AI models that leverage one of the world's largest clinical and molecular datasets—transforming patient care at a massive scale.

Responsibilities

• Design and train state-of-the-art models utilizing multi-modal data, including pathology slides (WSI), genomic profiles (DNA/RNA), spatial omics, and longitudinal patient records.
• Develop sophisticated AI solutions to support biomarker discovery, therapy outcome prediction, and the advancement of Companion Diagnostics (CDx) in collaboration with life sciences companies.
• Ensure all AI products meet stringent regulatory guidelines and quality standards for healthcare applications.
• Maintain Tempus’s position as a thought leader by publishing original research in high-impact venues and engaging with the global AI research community.
• Lead end-to-end development of machine learning models, from research and experimentation to validation and production deployment.

Qualifications

• Ph.D. in Computer Science or a related quantitative field.
• 1+ years of industry experience leading end-to-end development of machine learning models.
• Demonstrated expertise in large-scale deep learning and training production-grade models; experience in computer vision and multimodal modeling (pathology, multi-omics, etc.) is preferred.
• Prior work in medical or healthcare AI is highly valued but not required.
• A strong track record of peer-reviewed publications in leading machine learning, computer vision, or medical/healthcare AI venues.
• Proficiency in Python and the modern deep learning stack (e.g., PyTorch). Strong product-level coding skills for model development and a solid understanding of industry-standard software engineering practices.

We value diverse perspectives and recognize that outstanding talent doesn't always follow a linear path. If you are passionate about this work and believe you have what it takes to thrive here, please apply even if you do not precisely match all the qualifications above.

Pay

CHI: $125,000-$185,000
NYC/SF: $150,000-$190,000

The expected salary range above is applicable if the role is performed from California and may vary for other locations (Colorado, Illinois, New York). Actual salary may vary based on qualifications and experience.

Benefits

• Full range of benefits, which may include incentive compensation and restricted stock units.
• Medical and other benefits depending on the position.