Scientist, Product Biochemistry

What You'll Do

• Develop analytical methods and purification protocols to support extended characterization of therapeutic proteins and gene therapy vectors
• Conduct biochemical/biophysical characterization to support development, regulatory submissions, and commercialization
• Apply DOE, advanced statistics, and risk assessments to evaluate and optimize methods and processes
• Design and execute experiments to enrich, purify, and characterize size/charge variants, complexes, and high-concentration formulations
• Independently operate U/HPLCs and AKTA FPLCs, and perform capillary-based electrophoresis
• Integrate learnings from internal data and external literature to make science-based study design recommendations
• Author high-quality technical documents (protocols, reports, memos), contribute to regulatory sections and publications, and ensure timely documentation of experiments in accordance with established SOPs and guidelines
• Document experiments, results, and findings in the electronic laboratory notebook, and present work at group and department meetings
• Maintain instruments, troubleshoot instrumental/experimental problems, order/maintain supplies, and improve lab/data workflows within your area of expertise

The Environment And Physical Rhythms Of This Role

• This is a hands-on, on-site laboratory role requiring independent operation of specialized analytical instrumentation and the ability to manage multiple priorities in a fast-moving R&D environment
• Flexibility to thrive in a fast-paced, team environment while also working independently across multiple projects, and to mentor others while contributing to a safe, efficient, and inclusive lab environment, is required

Let's Find Out If We're A Fit

• BS/MS in Biochemistry, Biophysics, Engineering, or a related field, with 8-10+ years of relevant industry experience
• Strong lab skills in protein separation, purification, and tangential flow filtration (TFF), and skills in protein/product identification using mass spectrometry
• Excellent oral and written communication skills and evidence of teamwork
• Strong initiative to complete tasks, learn new technologies, and demonstrate a commitment to continuous learning
• Able to communicate clearly, transparently, and in a timely manner with key stakeholders