Scientist Nucleic Acids Computational Biology

About the role

Bristol Myers Squibb is seeking a highly motivated and innovative scientist to drive advances at the intersection of RNA biology, computational modeling, and machine learning. The ideal candidate will have a strong foundation in RNA biology, proficiency with RNA secondary structure analysis tools, and hands-on programming experience in Python or R.

Responsibilities

• Design and implement custom mRNA optimization strategies to fine-tune expression, stability, and immunogenicity of the RNA payload.
• Innovate on mRNA designs by utilizing scientific literature to implement novel design principles.
• Collaborate with experimental biologists and molecular biologists to generate and analyze NGS data from RNA structure probing and other RNA biology-directed experiments.
• Lead cross-functional collaboration with therapeutic project teams to design studies, set experimental priorities, and validate computational discoveries.

Requirements

• Bachelor's Degree in Computational Biology, Physics, Computer Sciences or related field, or equivalent experience.
• Ph.D. in Computational Biology, Physics, Computer Sciences or related field, or equivalent experience.
• Experience with diverse RNA sequencing modalities beyond standard RNA-seq.
• Utilization of computational modeling to evaluate nucleic acid functions.
• Experience with one or more programming or scripting languages such as Python and R.
• Experience with cloud computing platforms and high-performance computing environments.

Preferred Qualifications

• Experience with applying AI/ML models to NGS datasets to elucidate RNA biology.
• Dissection of RNA secondary structure prediction concepts and computational tools.

Qualifications

• 5+ years of academic / industry experience, or Master's Degree with 3+ years of academic / industry experience, or PhD with no experience required.

Benefits

• Competitive compensation package including discretionary bonus, Incentive Stock Options, 401k plan, health, dental, and vision benefits, life and disability insurance, and free parking.
• Unlimited paid vacation, 11 paid national holidays, and 3 optional holidays.
• Wellbeing Support, Financial Well-being and Protection, Work-life Benefits, and Uniquely Interesting Work, Life-changing Careers.