Scientist – LNP Formulation

Schedule

Full-time, Monday–Friday, 8:00 AM–5:00 PM EST (first shift). Fully onsite at customer site in Boston, MA; relocation assistance not provided. Must be legally authorized to work in the U.S. without sponsorship and able to pass a comprehensive background check including drug screening.

Responsibilities

• Manufacture small and large scale LNP formulations including production, purification and analysis of LNPs using industry standard protocols.
• Meet established deadlines.
• Maintain clear and complete ELN-based experimental records.
• Follow SOPs to generate and maintain thorough and accurate documentation.
• Proven ability to adapt to strategic changes in a dynamic and fast-paced drug development environment.
• Willingness to learn new techniques and expand technical capabilities.
• Ability to work collaboratively within a team.

Qualifications

• Bachelor's degree in lab sciences such as Chemistry, Biochemistry, Material Science, Immunology, Biology, Molecular Biology or similar.
• Scientist: Previous experience that provides the knowledge, skills, and abilities to perform the job (comparable to 2+ years') OR Master's Degree.
• In some cases, an equivalency consisting of a combination of appropriate education, training and/or directly related experience will be considered sufficient.

Skills

• Hands-on experience in various LNP formation mixing technologies, including but not limited to various microfluidic mixing and Impingement Jet Mixing devices.
• Hands-on experience and knowledge on LNP purification techniques including TFF.
• Hands-on experience in LNP process development experiments focused on maintaining product quality.
• Experience on LNP formulation manufacturing for non-human primate studies.
• Complete knowledge and experience on various LNP analytics including Size, PDI, RNA encapsulation, Osmolality, and Endotoxin measurement.
• Exemplary work ethic and commitment to scientific rigor.
• Strong communication skills.

Working Environment

• Able to communicate, receive, and understand information and ideas with diverse groups of people in a comprehensible and reasonable manner.
• Able to work upright and stationary and/or standing for typical working hours.
• Able to lift and move objects up to 25 pounds.
• Able to work in non-traditional work environments.
• Able to use and learn standard office equipment and technology with proficiency.
• May have exposure to potentially hazardous elements, including infectious agents, typically found in healthcare or laboratory environments.
• Able to perform successfully under pressure while prioritizing and handling multiple projects or activities.
• Adherence to all Good Manufacturing Practices (GMP) safety standards; laboratory setting.

Pay

Hourly range: $35.00–$40.50 (Massachusetts). Eligible for variable annual bonus based on company, team, and/or individual performance.

Benefits

• Choice of national medical, dental, and vision plans, including health incentive programs
• Employee assistance and family support programs, including commuter benefits and tuition reimbursement
• At least 120 hours paid time off (PTO), 10 paid holidays annually, paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave), accident and life insurance, and short- and long-term disability
• Retirement and savings programs, including competitive 401(k) U.S. retirement savings plan
• Employees' Stock Purchase Plan (ESPP) with discounted company stock purchase