Scientist II – Translational Sciences (Contract)

Responsibilities

• Plan, design and execute in vitro and in vivo experiments related to Pliant’s novel drug delivery platform
• Design and manage experiments run at external CROs to advance our understanding of tissue-specific drug delivery platforms across multiple disease indications
• Advance drug discovery programs by interacting with and communicating results to interdisciplinary team
• Manage and supervise the day-to-day work of one or more Research Associates including training and coaching
• Contribute to development and adoption of new technologies
• Provide support for various research team projects using dynamic prioritization
• Prepare detailed protocols, document experimental observations, analyze data promptly, and maintain accurate, well-organized records
• Evaluate and clearly report experimental results to research team on a routine basis

Qualifications

• PhD in Molecular Biology, Biochemistry, Immunology, Cell Biology or related field, with 2+ years industry experience in drug development
• Expertise in cardiovascular, autoimmune, immuno-oncology or fibrotic disease preferred
• Experience designing wet-lab assays that utilize basic cell biology laboratory procedures including cell culture, cell transfection, qRT-PCR, ELISA, flow cytometry/FACS, Western blot, fluorescent microscopy, immunofluorescence-based staining, etc.
• Having experience working with Operetta CLS High content imaging and Sony Sorter is a plus
• Experience working with iPSC cells is a plus
• Experience designing, managing and analyzing results from in vivo studies evaluating drug PD/efficacy
• Experience with evaluating CROs and managing in vivo and/or in vitro work performed by CROs
• Strong evidence of conceptual thinking, active follow-through, and vigorous scientific curiosity
• Exceptional interpersonal, verbal, and written communication skills
• Candidate should be flexible with rapid changes in schedule based on scope/prioritization of projects
• Candidate should exhibit strong, positive attitude for teamwork and learning
• Ability to thrive in a culture of respect, accountability, transparency, and collaboration

Pay

The hourly rate for this role is $71/hr – $79/hr. Individual pay may vary based on additional factors, including, and without limitation job-related skills, experience, work location and relevant education or training.