Scientist I/II – LC-MS/MS Bioanalysis

About the role

As a Scientist I/II – LC-MS/MS Bioanalysis at Pharmaron, a global CRO/CDMO with over 25,000 employees supporting drug discovery through manufacturing, you will develop, optimize, troubleshoot, and validate bioanalytical methods supporting DMPK and regulated studies. You'll work with advanced LC‑MS/MS and high‑resolution mass spectrometry platforms while gaining exposure to a broad range of therapeutic modalities—from traditional small molecules to peptides, oligonucleotides, PROTACs, biologics, and emerging therapies. This role is ideal for an early‑career bioanalytical scientist seeking to expand beyond routine sample analysis and develop deeper expertise in method development, complex bioanalysis, scientific problem‑solving, and study execution within a global CRO/CDMO environment. Position located in Exton, PA (on‑site).

Responsibilities

• Develop, optimize, troubleshoot, and validate LC-MS/MS bioanalytical methods supporting drug discovery and development programs.
• Perform bioanalytical sample analysis for DMPK, method development, validation, and regulated studies.
• Operate LC-MS/MS and HPLC platforms and gain exposure to advanced mass spectrometry technologies.
• Design and execute scientifically sound experiments aligned with client objectives, study requirements, and internal quality standards.
• Process, analyze, interpret, and report bioanalytical data while identifying and resolving technical challenges.
• Review and execute study protocols and ensure accurate documentation of experimental procedures, results, and conclusions.
• Author and contribute to protocols, validation reports, technical summaries, study reports, and other scientific documentation.
• Support GLP and regulated bioanalytical activities in accordance with applicable procedures and quality requirements.
• Collaborate with scientists, project teams, management, Business Development, and clients to support successful project execution.
• Participate in scientific project reviews, technical discussions, and continuous improvement initiatives.
• As experience develops, take on increasing scientific ownership and opportunities to support studies in a Principal Investigator and/or Study Director capacity, as appropriate.

Requirements

• Bachelor's degree or higher in Chemistry, Pharmaceutical Sciences, Biochemistry, Life Sciences, or a related scientific discipline.
• 1–3+ years of relevant bioanalytical laboratory experience; position level will be determined based on experience and demonstrated technical capabilities.
• Hands-on experience with LC-MS/MS bioanalysis, including exposure to method development, optimization, validation, and/or sample analysis.
• Understanding of chromatographic and mass spectrometric principles.
• Strong analytical thinking and ability to troubleshoot scientific and technical challenges.
• Ability to accurately analyze, interpret, document, and communicate scientific data.
• Strong organizational skills and attention to detail.
• Ability to manage multiple priorities and work effectively in a fast-paced, collaborative scientific environment.

Qualifications

• Experience developing and validating LC-MS/MS bioanalytical methods.
• Experience working within a GLP or regulated bioanalytical environment.