Scientist I/II

About the role

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on LinkedIn, Facebook, Instagram, X and YouTube.

The Quantitative, Translational & ADME Sciences (QTAS) Department at AbbVie, Inc. in North Chicago, IL is seeking a Scientist I to join the Non-Regulated Bioanalysis group. This role supports high-throughput processing of samples from biological matrices and LC-MS/MS-based bioanalysis. The ideal candidate will have experience in bioanalytical sample preparation using a range of extraction techniques, operational workflows, data analysis, review, and reporting. This position is well suited for a detail-oriented, motivated scientist who thrives in a fast-paced, collaborative environment and is committed to delivering high-quality results across multiple projects under tight deadlines. The role also involves partnering with cross-functional teams to align bioanalytical processes with scientific and business needs.

Responsibilities

• Support LC-MS/MS-based PK/PD, efficacy, and exploratory toxicology bioanalytical studies
• Conduct and optimize sample extraction using protein precipitation, liquid/liquid extraction, or solid-phase extraction methods
• Operate and troubleshoot robotic systems (Hamilton, Tecan) and LC-MS/MS platforms (Leap/CTC PAL autosamplers, Agilent HPLCs, Sciex 5500/6500 triple quadrupole mass spectrometers) and software such as Discovery Quant, Analyst, SciexOS, and MassHunter
• Troubleshoot pre-analytical and bioanalytical issues
• Maintain accurate documentation of work, including LIMS records, electronic notebooks, test methods, and protocols
• Collaborate with teams across Discovery and QTAS to support bioanalysis
• Train and mentor junior scientists as needed

Qualifications

• Bachelors degree with 5 years of experience, or Masters degree with 2 years of experience, in Chemistry, Analytical Chemistry, or a related field
• Hands-on experience in bioanalysis of small molecules, peptides, and large molecules in the pharmaceutical industry, including sample preparation and method development
• Strong interpersonal skills with the ability to work independently and collaboratively in a high-throughput setting
• Experience operating automated liquid handling robotic platforms such as Hamilton or equivalent systems
• Experience operating CTC-PAL and Agilent liquid chromatography instruments, as well as LC-MS/MS platforms such as ABSciex triple quadrupole mass spectrometers or equivalent systems
• Experience with electronic laboratory notebook software and Laboratory Information Management Systems (LIMS)
• Strong instrument and assay troubleshooting skills
• Experience with process development or optimization preferred

Benefits

• Paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) for eligible employees.
• Eligible to participate in short‑term incentive programs.