Scientist I, Cell and Molecular Biologist

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience — and products and services in our Allergan Aesthetics portfolio.

About the role

AbbVie Oncology Discovery is seeking a highly motivated and experienced cancer cell biologist to support drug discovery projects in our in vitro cancer biology team with a focus on antibody-drug conjugates. The candidate will work closely with a team of experienced scientists to develop and optimize key pharmacological, biochemical, and cell-based assays to support multiple programs.

Responsibilities

• Design and execute in vitro studies to assess novel antibody-drug conjugates.
• Analyze and interpret experiments and present data to the broader project team and group meetings. Propose relevant follow-up experiments as needed.
• Troubleshoot and/or optimize experimental procedures as needed to further the program goals.
• Contribute to the preparation of data packages for scientific publications, regulatory documents, and patent applications.
• Work independently in a fast-paced, multi-tasking environment as part of a diverse research team.
• Collaborate with cross-functional teams to advance programs from early discovery to preclinical development.

Qualifications

• Required: Bachelor’s Degree with 5 years of experience, or Master’s Degree with two years of experience in molecular/cellular biology, cancer biology, pharmacology, or related discipline with significant research experience.
• Proficiency in tissue culture, cellular & biochemical in vitro assay development, and molecular biology techniques (e.g., Western blotting/WES, ELISA, proliferation assays, FACS, lentivirus).
• Background in drug discovery, pharmacology, and assay development.
• Organizational skills and experience with computer programs, including Microsoft Excel, PowerPoint, GraphPad, FlowJo, etc.
• Preferred: Understanding and application of methods of antibody characterization and/or antibody-drug conjugates.
• Preferred: Knowledge and experience with a broad range of assays to characterize targeted protein degradation.
• Preferred: Familiarity and proficiency with available genomic/transcriptomic datasets (TCGA, DepMap, CCLE, etc.).

Skills

• Builds strong relationships with peers and cross-functionally with partners outside of the team to enable higher performance.
• Learns fast, grasps the "essence," and can change course quickly where indicated.
• Raises the bar and is never satisfied with the status quo.
• Creates a learning environment, open to suggestions and experimentation for improvement.
• Embraces innovation and manages to reality.

Benefits

• Comprehensive package of benefits including paid time off (vacation, holidays, sick).
• Medical, dental, and vision insurance.
• 401(k) to eligible employees.
• Eligibility to participate in short-term incentive programs.

The compensation range for this role is based on the job grade and may vary depending on geographic location. Individual compensation will be determined based on various factors.