Scientist I, Bioanalytics

Key Responsibilities

• Support LC-MS/MS-based PK/PD, efficacy, and exploratory toxicology bioanalytical studies
• Conduct and optimize sample extraction using a range of extraction techniques, operational workflows, data analysis, review, and reporting
• Operate and troubleshoot robotic systems (Hamilton, Tecan) and LC-MS/MS platforms (Leap/CTC PAL autosamplers, Agilent HPLCs, Sciex5500/6500 triple quadrupole mass spectrometers) and software such as Discovery Quant, Analyst, SciexOS, and MassHunter
• Troubleshoot pre-analytical and bioanalytical issues
• Maintain accurate documentation of work, including LIMS records, electronic notebooks, test methods, and protocols
• Collaborate with teams across Discovery and QTAS to support bioanalysis

Qualifications

• Bachelor’s degree with 5 years of experience, or Master’s degree with 2 years of experience, in Chemistry, Analytical Chemistry, or a related field
• Hands-on experience in bioanalysis of small molecules, peptides, and large molecules in the pharmaceutical industry, including sample preparation and method development
• Strong interpersonal skills with the ability to work independently and collaboratively in a high-throughput setting
• Experience operating automated liquid handling robotic platforms such as Hamilton or equivalent systems
• Experience operating CTC-PAL and Agilent liquid chromatography instruments, as well as LC-MS/MS platforms such as ABSciex triple quadrupole mass spectrometers or equivalent systems
• Experience with electronic laboratory notebook software and Laboratory Information Management Systems (LIMS)
• Strong instrument and assay troubleshooting skills
• Experience with process development or optimization preferred