Scientist I, Analytical Development

Role Overview: The Scientist I will lead method development in the Analytical Development and Quality Control labs, focusing on biophysical characterization of viral vector particles, especially AAV. This hands-on role involves designing and executing experiments, developing and validating analytical and QC assays, and operating under cGMP standards. The position requires expertise in HPLC, including CAD and MALS detectors, and experience with Astra software for SEC-MALS analysis. The scientist will collaborate across departments, assist with technology evaluation, and support tech transfer and electronic record systems. Key Responsibilities Develop and establish HPLC-based methods for AAV vector characterizationOperate and troubleshoot HPLC equipmentUtilize Astra and OpenLab software for data analysisMaintain familiarity with bioassay methods such as flow cytometry, ELISA, qPCR, ddPCRQualify and validate analytical methods supporting cGMP testingAssist with training, project planning, and cross-department collaborationContribute to electronic record-keeping system setupEnsure high-quality deliverables and foster a collaborative scientific environment Qualifications & Skills BS in a scientific/technical discipline2-4 years CRO/CDMO experience in bioanalytical method development, qualification, validation, and transferHands-on experience with MALS and CAD detectors in AAV analyticsKnowledge of LC-MS assay developmentStrong troubleshooting, communication, and leadership skillsAbility to manage multiple projects and adapt to changing needs Additional Requirements: Ability to work in BSL2 environments, physical capacity to lift up to 25 pounds, and willingness to undergo background checks. Must demonstrate high initiative, adaptability, and problem-solving abilities.