Scientist, Dissolution & Biopharmaceutical Modeling

About the role

Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.

Responsibilities

• Developing analytical methods and conducting experiments to aid early clinical formulation development to enable drug delivery of a broad range of synthetic drug molecules.
• Collaborating with formulation scientists to design experiments and guide selection and characterization of formulations for pre-clinical and early clinical drug candidates.
• Partnering with biopharmaceutical modeling scientists, analytical chemists, pharmaceutical scientists, and engineers to identify the appropriate drug form, formulation, and process characteristics that provide the desired drug product performance.
• Identifying and mitigating technical risks for the performance and production of clinical and commercial drug products.
• Executing with attention to safety, quality, regulatory, GLP/GMP, and legal requirements for all activities.
• Authoring key regulatory documents, demonstrating appropriate understanding of product performance control strategy, and biopharmaceutics risk mitigation for clinical trials and product commercialization.
• Embrace diverse thought, background, and experience to deliver innovative solutions.
• Possess strong communication (oral, written), organizational, and leadership skills.
• Engaging and influencing the external scientific community to foster collaborations for innovation and to advance Lilly’s internal portfolio.

Requirements

• B.S. in Chemistry, Biochemistry, Pharmaceutical Science, or other directly related discipline (e.g., Material Science)
• Understanding of analytical techniques and methods for characterizing physicochemical properties of drug molecules and performance of drug products (e.g., HPLC, UV, NIR, dissolution)
• Strong leadership, supervisor, teamwork, communication and writing skills

Qualifications

• Basic Requirements
• Industry, research or internship experience relevant to the position is strongly preferred
• Knowledge of biopharmaceutics and pharmacokinetic principles, formulation development and pharmaceutical material sciences, and drug product factors impacting in vivo performance and manufacture
• Basic understanding of regulatory aspects pertaining to development and clinical testing of drug products
• General understanding of techniques and instrumentation used in characterization of pharmaceutical drug products, especially dissolution and other product performance tests

Skills & Preferences

• Industry, research or internship experience relevant to the position is strongly preferred
• Knowledge of biopharmaceutics and pharmacokinetic principles, formulation development and pharmaceutical material sciences, and drug product factors impacting in vivo performance and manufacture
• Basic understanding of regulatory aspects pertaining to development and clinical testing of drug products
• General understanding of techniques and instrumentation used in characterization of pharmaceutical drug products, especially dissolution and other product performance tests

Benefits

Actual compensation will depend on a candidate's education, experience, skills, and geographic location. The anticipated wage for this position is $65,250 - $148,500. Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance).

In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).

Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.