Scientist, Computational Chemist & MLOps Engineer
Arrowhead Pharmaceuticals · Madison, WI · 3 wk ago
On-siteAnalyst$100k/yrFull-time
Responsibilities
- Develop and apply statistical and machine learning models to experimental datasets
- Design, maintain, and optimize scientific databases and data processing pipelines
- Build reproducible computational workflows for bioinformatics and drug discovery applications
- Analyze high-dimensional biological datasets and communicate findings to multidisciplinary teams
- Contribute production-quality Python code and maintain version-controlled scientific software
- Operate effectively in Linux/HPC environments, including remote systems and cloud-based infrastructure
- Write clear, maintainable, and testable scientific code
- Debug complex computational and data issues independently
- Operate effectively in terminal/Linux-native workflows
- Apply statistically rigorous thinking to experimental interpretation
- Maintain reproducibility and software engineering discipline in research environments
- Partner with scientists across biology, chemistry, bioinformatics, and computational research groups
- Support development of internal computational platforms and modeling infrastructure
- Document workflows, analyses, and software according to reproducible research standards
- Mentor junior team members and contribute to technical best practices
Requirements
- Scientist I: Bachelor’s or Master’s degree in Bioinformatics, Biostatistics, Computational Biology, Computer Science, Data Science, Applied Mathematics, or related field
- Strong programming experience in Python
- Experience working in Linux command-line environments
- Foundational understanding of statistics and machine learning methods
- Experience handling structured and unstructured biological datasets
- Familiarity with source control tools such as Git
- Scientist III (In addition to the above): Advanced degree (PhD preferred) or equivalent industry experience
- Demonstrated history of leading computational projects independently
- Strong background in applied statistics, predictive modeling, and experimental data interpretation
- Experience mentoring scientists or leading technical initiatives
- Ability to translate ambiguous scientific problems into robust computational solutions
Preferred
- Experience with predictive modeling and/or deep learning methods
- Familiarity with modern ML tooling and model evaluation methodologies
- Experience in therapeutic design, RNA biology, genomics, or laboratory experience
- Experience with bioinformatics workflows and sequence-based analysis
- Experience working with large-scale biological or omics datasets
- Experience with distributed computing systems
- Experience operating in collaborative software development environments