Jobs · Analyst · Massachusetts

Scientist, Chemistry and Delivery Science

BioSpace · Cambridge, MA · 2 mo ago
Analyst$109k–$175k/yrFull-time

We are seeking a highly motivated and innovative Scientist to join our multidisciplinary team focused on advancing next-generation lipid nanoparticle (LNP) delivery technologies. In this role, you will drive the design, development, and optimization of LNP formulations that enable the delivery of transformative therapeutic modalities. The successful candidate will combine scientific rigor with creativity, leveraging a deep curiosity for understanding the fundamental principles of LNP self-assembly, structure-function relationships, and delivery performance.

Responsibilities

  • Design, execute, and interpret complex experiments to establish structure–activity relationships (SAR) that drive the rational design, optimization, and development of next-generation lipid nanoparticle (LNP) formulations.
  • Develop and comprehensively characterize novel formulations using a broad range of biophysical, physicochemical, and analytical techniques to evaluate performance, stability, and delivery attributes.
  • Conduct in-depth scientific literature reviews and competitive landscape assessments to identify emerging formulation technologies, translate new insights into experimental strategies, and implement innovative protocols that accelerate research objectives.
  • Maintain rigorous and well-documented experimental records in electronic laboratory notebooks (ELNs), ensuring data integrity, reproducibility, and compliance with organizational standards.
  • Drive scientific innovation through critical data analysis and collaborative problem-solving, contributing to the advancement of platform technologies and the progression of therapeutic product candidates.
  • Effectively communicate scientific findings and strategic recommendations through presentations, technical reports, and cross-functional discussions, while serving as an active contributor to project teams and scientific forums.
  • Partner closely with multidisciplinary teams across formulation, analytical development, biology, and process development to translate scientific discoveries into impactful therapeutic solutions.
  • Establish and execute high-throughput experimental platforms to rapidly evaluate formulation, process, and biological performance across large candidate libraries.
  • Develop and implement statistical models and AI/ML approaches to analyze complex datasets, uncover structure–property relationships, predict outcomes, and accelerate formulation and process optimization.

Requirements

  • PhD in Biochemistry, Chemistry, Chemical Engineering, Biomedical Engineering, Pharmaceutical Sciences, or a related discipline with 0–3 years of relevant industry experience, or an MS degree with 5+ years of industry experience in drug delivery, formulation development, or a related field.
  • Strong scientific foundation in nanoparticle design, formulation development, and characterization, with experience in lipid nanoparticles (LNPs), nucleic acid delivery systems, or other advanced drug delivery technologies preferred.
  • Demonstrated ability to design rigorous experiments, analyze complex datasets, and generate actionable scientific insights that advance research programs and inform strategic decisions.
  • Passion for exploring emerging therapeutic modalities and innovative delivery approaches, coupled with the creativity and intellectual curiosity to challenge conventional thinking and develop novel solutions.
  • Proven ability to work independently while thriving in highly collaborative environments, effectively balancing multiple priorities in a fast-paced research setting.
  • Strong commitment to scientific excellence, innovation, and execution, with a track record of delivering high-quality results and driving projects forward.
  • Excellent critical thinking, problem-solving, and data interpretation skills, with the ability to connect experimental findings to broader scientific and translational objectives.
  • Strong written and verbal communication skills, including experience presenting scientific data, preparing technical reports, and contributing to cross-functional discussions.
  • Exceptional interpersonal skills with a demonstrated ability to build productive partnerships, mentor colleagues, and foster a collaborative team culture.
  • Experience working effectively in a cross-functional, matrixed environment, partnering with scientists and stakeholders across formulation, analytical development, biology, process development, and other disciplines to advance therapeutic programs.

Pay

The salary range for this role is $109,200.00 - $174,600.00. An individual’s position within the salary range will be based on several factors including, but not limited to, specific competencies, relevant education, qualifications, certifications, experience, skills, performance, and business or organizational needs. The successful candidate may be eligible for an annual discretionary bonus, other incentive compensation, or equity award, subject to company plan eligibility criteria and individual performance.

Benefits

  • Competitive healthcare, plus voluntary benefit programs to support your unique needs.
  • A holistic approach to well-being, with access to fitness, mindfulness, and mental health support.
  • Family planning benefits, including fertility, adoption, and surrogacy support.
  • Generous paid time off, including vacation, volunteer days, sabbatical, global recharge days, and a discretionary year-end shutdown.
  • Savings and investments to help you plan for the future.
  • Location-specific perks and extras.

Schedule

This role follows a 70/30 work model, requiring 70% in-office presence to foster innovation, teamwork, and direct mentorship.

About the Company

Since our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world. By living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture. Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities. We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S.

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