Scientist, Biology

About the role

Our mission is to develop therapies that empower the immune system to combat neurodegeneration and our team is focused on developing treatments for some of the most challenging diseases facing our society. By harnessing advancements in genetics, immunology and neuroscience, we are pioneering the development of potential therapies to counteract the devastating progression of neurodegeneration. We are supported in this mission by experienced and accomplished scientists and clinicians, a novel portfolio of programs, leading healthcare investors, and pharma company partners, who share in our commitment to bettering the lives of patients and realizing a world where we make brain disorders history.

Responsibilities

• Design and execute in vitro pharmacology studies using iPSC‑derived cellular models (induced neurons, induced microglia, co‑culture and triple‑culture systems).
• Build and optimize disease‑relevant cellular models of neurodegenerative disease, including Alzheimer’s disease, to enable proof‑of‑concept (POC) and mechanism‑of‑action (MOA) studies.
• Collect and process cell lysates, media, rodent brain, and other biological samples; perform downstream biochemical and cellular analyses.
• Analyze, interpret, document, and communicate results while maintaining accurate experimental records, protocols, and data in our electronic lab notebook.
• Collaborate across Biology, ADPE, and Preclinical teams to advance programs.
• Identify opportunities to integrate innovative technologies, especially AI, to expedite programs, improve scientific workflows, and save valuable resources.
• Work with advanced cellular models, process in vivo and in vitro samples, and generate high‑quality data that inform pharmacokinetics/pharmacodynamics (PK/PD), efficacy, safety, POC, and MOA studies.

Requ