Jobs · OTHR · California

Scientist

Russell Tobin · San Diego, CA · 1 wk ago
On-siteOTHR$40–$45.45/hrFull-time

About the role

Scientist Russell Tobin is partnering with a biopharmaceutical company to identify a Scientist for an opportunity in San Diego, CA.

Responsibilities

  • Execute and optimize the formulation and characterization of targeted and non-targeted lipid nanoparticles (LNPs) for nucleic acid delivery.
  • Formulate LNPs encapsulating mRNA, siRNA, or DNA for in vitro and in vivo studies.
  • Execute Design of Experiments (DoE) screening campaigns to optimize LNP compositions and processing parameters.
  • Collaborate with cross-functional teams to support formulation requests and early-stage formulation development.
  • Support downstream processing activities, including cryoprotection, scale-up, and stability studies.
  • Maintain detailed laboratory records and documentation of formulation activities and results.
  • Analyze, interpret, and present experimental data to the formulation team.
  • Support laboratory operations, including inventory tracking, supply ordering, buffer preparation, and autoclaving.

Requirements

  • Bachelor's degree in Chemistry, Biochemistry, Chemical Engineering, or a related field with 4+ years of biopharmaceutical industry experience, OR Master's degree with 1+ years of industry experience.
  • Minimum 2 years of hands-on LNP formulation and nucleic acid encapsulation experience involving mRNA, siRNA, or DNA.
  • Experience with LNP characterization techniques, including Dynamic Light Scattering (DLS), Zeta potential, and RiboGreen assays.
  • Prior hands-on experience with targeted LNP preparation, including mAb-, Fab-, ScFv-, or VHH-coated LNPs, and immune cell delivery.
  • Strong proficiency in Microsoft Excel; experience with JMP, GraphPad Prism, or similar data analysis software is preferred.
  • Strong attention to detail with a demonstrated ability to generate reproducible experimental data.
  • Excellent organizational, communication, and teamwork skills.

Pay

  • $40/hr – $45.45/hr depending on experience

Schedule

  • 100% Onsite – San Diego, CA
  • Contract – 3 months with possibility of extension

Benefits

  • Comprehensive healthcare coverage (medical, dental, and vision plans)
  • Supplemental coverage (accident insurance, critical illness insurance, and hospital indemnity)
  • 401(k)-retirement savings
  • Life & disability insurance
  • Employee assistance program
  • Legal support
  • Pet insurance
  • Employee discounts with preferred vendors

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