Jobs · OTHR · California

Scientist 1, Single Cell Assay Development

10x Genomics · Pleasanton, CA · 2 wk ago
On-siteOTHR$123k–$167k/yrFull-time

About the role

We are seeking a motivated and driven scientist to join the Single Cell Biology group in a full-time role focused on the development and optimization of single cell assays. This role executes hands-on molecular biology work to develop, test, and refine 10x single cell workflows, and supports advanced troubleshooting for internal teams and customers. You will work in a fast-paced, multidisciplinary environment alongside colleagues in Molecular/Cell Biology, Chemistry, Fluidics, and Computational Biology. Candidates must have hands-on experience with 10x single cell assays, a strong foundation in NGS and molecular biology techniques, and the ability to apply that knowledge to troubleshoot complex systems.

Responsibilities

  • Perform standard and custom experiments to develop, test, and improve single cell assay workflows, including sample processing, library preparation, sequencing, and data analysis
  • Prepare high-quality NGS libraries using established molecular biology protocols
  • Contribute to the design, testing, and troubleshooting of new assay components and existing systems
  • Master the use of existing tools and defined protocols, and identify opportunities to improve them
  • Conceive of and develop new tools and methods to support assay development
  • Analyze and interpret experimental data to draw conclusions and determine next steps
  • Begin to collaborate cross-functionally with R&D, Support, and Marketing to advance assay development priorities
  • Contribute to project plans and sub-task timelines for assigned workstreams

Requirements

  • B.S./M.S. or Ph.D. in chemistry, molecular biology, biochemistry, cell biology, or a related field
  • B.S. with 4+ years, M.S. with 2+ years, or Ph.D. with 0–2 years of relevant biotechnology or pharmaceutical industry experience
  • Hands-on experience with molecular biology techniques, including nucleic acid extraction, PCR/qPCR, and NGS library preparation
  • Direct experience with Next-Generation Sequencing (NGS) workflows and standard molecular biology techniques
  • Experience with experimental design and statistical data analysis
  • Ability to perform complex multi-step experiments with diligent attention to planning, organization, hands-on technique, and record keeping
  • Strong collaboration and communication skills, with the ability to manage competing priorities
  • Desire to work in a flexible, fast-paced environment

Qualifications

  • Hands-on experience running 10x single cell assays
  • Experience working with challenging clinical sample types (e.g., FFPE tissue, primary tumor cells, low-input samples)
  • Familiarity with the product development lifecycle, including new product introduction and formal product testing (e.g., verification and validation)

Pay

Salary range: $123,100 - $166,500. Base pay is one component of the total compensation package.

Benefits

  • Eligible for equity grants
  • Comprehensive health and retirement benefit programs
  • Annual bonus program or sales incentive program

Schedule

Full-time position.

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